Programmed 2006 Isuzu I-350 PCM Engine Computer | 12606374

Get Your Isuzu Running Right, Guaranteed.

Tired of unpredictable stalling and a persistent check engine light? This plug-and-play PCM is the solution. We pre-program it to your truck’s exact VIN, so you can get back on the road with confidence and peace of mind. Stop worrying and start driving. Order your direct-fit replacement now!

$184.95

+11.99 USPS Priority Shipping

Availability: In stock



Guaranteed Safe Checkout

Is Your Isuzu I-350 Running Unreliably?

If your 2006 Isuzu I-350 is experiencing frustrating issues like stalling, a persistent check engine light, rough idling, or even a no-start condition, a failing Powertrain Control Module (PCM) is often the culprit. As the central computer for your truck’s engine, a faulty PCM can disrupt everything from fuel delivery to transmission shifting, making your vehicle unreliable and unsafe. Don’t let a bad module keep you off the road; we have the precise, pre-programmed solution you need.

Common Symptoms of a Failing PCM & Your Direct-Fit Solution

A failing engine computer can manifest in numerous ways. You might be seeing diagnostic trouble codes (DTCs) like P0601, P0602, P0606, or other communication-related errors. You may also notice a sudden drop in fuel economy, erratic engine behavior, or harsh shifting. This unit is the definitive fix for these problems. We take the guesswork and high dealership costs out of the equation by providing a direct-fit 2006 Isuzu I-350 Programmed PCM Engine Computer that arrives ready for installation.

  • ✔ Peak Performance & Efficiency: We program this module with the newest GM-certified software using your truck’s specific VIN. This ensures optimal engine performance, correct fuel mapping, and smooth transmission control right out of the box.
  • ✔ True Plug-and-Play Installation: Because this unit arrives programmed specifically for your Isuzu, it’s a direct-fit, plug-and-play replacement. No expensive trips to the dealer for programming are required, saving you time and money.
  • ✔ Guaranteed Compatibility: This PCM is a direct replacement for a wide range of original part numbers, including 12606374, 12597521, 12588650, and many others listed, ensuring a perfect match for your vehicle.
  • ✔ Tested for Reliability: Every module undergoes a thorough inspection and testing process to ensure it meets or exceeds original equipment standards for durability and function, giving you a dependable part for your workhorse truck.
  • ✔ Purchase with Confidence: This unit is backed by our one-year replacement warranty.

A Word From Our Master Tech: Before you install your new PCM, take 5 minutes to check your truck’s battery terminals and main ground connections (engine block to chassis, battery to chassis). A loose or corroded ground can cause voltage issues that damage sensitive electronics and can even mimic the symptoms of PCM failure. Ensuring your electrical foundation is solid is the key to a lasting repair and protecting your new investment.

By providing us with your VIN during checkout, you ensure you receive a perfectly matched 2006 Isuzu I-350 Programmed PCM Engine Computer. This critical step allows us to flash the module with the correct calibration files for your truck’s specific options, restoring the performance and reliability you depend on every day. Get your truck back to work with this simple, effective solution.

Frequently Asked Questions

Do I need to do any programming myself?

No. This module arrives pre-programmed to your vehicle’s VIN. It is a plug-and-play solution. In some cases, a simple security relearn procedure may be required, which can typically be done without special tools and takes only a few minutes.

How do I provide my vehicle’s VIN?

You can add your 17-digit Vehicle Identification Number (VIN) to the notes section during checkout. If you forget, we will contact you via email after your purchase to request it before we ship your part.

Is this the correct PCM for my truck?

This unit fits the 2006 Isuzu I-350 and many other GM vehicles listed in the fitment guide. Please cross-reference your original part number with the numbers provided in the description. If you are unsure, contact us with your VIN, and we will be happy to verify compatibility for you.

What does the PCM actually do?

The Powertrain Control Module, or PCM, is the main computer that controls all aspects of your engine and transmission. It manages fuel injection, ignition timing, emissions systems, and automatic transmission shift points to ensure the vehicle runs efficiently and smoothly.

Will this fix my check engine light?

If your check engine light is caused by an internal failure of the old PCM (e.g., DTC P0601), then this replacement module will solve the problem. However, it’s always best to have the codes professionally diagnosed to ensure the PCM is the root cause and not a separate sensor or wiring issue.

What if my original part number isn’t on the list?

The part numbers listed are the most common, but there may be others. If your part number is not on the list but your vehicle is a 2006 Isuzu I-350, please contact us with your VIN. We can confirm if this 2006 Isuzu I-350 Programmed PCM Engine Computer is the correct replacement for you.

Condition

Refurbished

Year

Genuine OEM

Yes

MPN

12606374

Brand

GM

Year

2006

Model

isuzu-i-350

Hardware Type

Interchange part number

Manufacturer Part Number

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