Restore Your Truck’s Core Performance
Is your 2006 Isuzu I-350 running rough, refusing to start, or throwing confusing check engine lights? A failing Powertrain Control Module (PCM) is often the culprit, acting as the brain of your vehicle’s engine and transmission. This replacement PCM isn’t just a part; it’s a direct solution, pre-programmed to your truck’s specific Vehicle Identification Number (VIN). We install the latest GM software updates before it ships, ensuring optimal engine performance, fuel efficiency, and transmission shifting right out of the box. Get your reliable workhorse back on the road with confidence.
Common Symptoms & Your Solution
If you’re experiencing any of the following issues, this module is the definitive fix you need. A faulty PCM can cause a cascade of problems that can be difficult to diagnose. By replacing the core component, you can eliminate the guesswork and solve the root cause. This is the solution for:
- Complete no-start or intermittent starting problems
- Poor or erratic automatic transmission shifting
- A persistent Check Engine Light (CEL)
- Diagnostic Trouble Codes (DTCs) such as P0601, P0602, or P0606
- Reduced fuel economy and engine performance
- Stalling, sputtering, or rough idling
By installing our expertly programmed 2006 Isuzu I-350 PCM 12606373, you are restoring the central command unit responsible for your truck’s dependability.
Features & Benefits
- ✔ VIN-Programmed for Your Truck: Arrives ready for a true plug-and-play installation, minimizing downtime and eliminating the need for expensive dealership programming.
- ✔ Loaded with Latest GM Updates: We flash the module with the most current software, ensuring all known bugs are fixed and performance is optimized.
- ✔ Restored Engine & Transmission Function: Regain the smooth shifting, consistent power, and reliability you depend on for work and daily driving.
- ✔ Direct-Fit Replacement: Guaranteed to fit and function perfectly with a wide range of GM trucks and SUVs, including the Colorado, Canyon, and Hummer H3. (See full fitment list).
- ✔ This unit is backed by our one-year replacement warranty.: We stand behind our programming and product quality, giving you peace of mind with your purchase.
Expert Insight: Why VIN-Specific Programming is Crucial
Many sellers offer generic or ‘unlocked’ modules, but this is a critical mistake for modern vehicles. Your truck’s PCM doesn’t just manage the engine; it communicates constantly with the transmission controller, anti-lock brake system (ABS), and the security system (Passlock/VATS). Our VIN-specific programming ensures these digital handshakes happen correctly. This prevents frustrating no-start security lockouts, improper transmission behavior, and ABS faults that can occur when using a non-programmed or incorrectly programmed computer. Getting a module flashed to your exact VIN is the only way to guarantee a seamless and correct repair.
Don’t let a faulty computer keep your truck sidelined. This is the most effective and reliable way to solve complex electronic issues and restore the performance you need. By providing your VIN at checkout, you ensure you receive a perfectly matched 2006 Isuzu I-350 PCM 12606373 ready to get the job done.
Frequently Asked Questions
What exactly does the PCM do?
The Powertrain Control Module (PCM) is your vehicle’s main computer. It controls all aspects of engine and transmission operation, including fuel injection, ignition timing, emissions systems, and automatic transmission shift points, to ensure peak performance and efficiency.
Is this part difficult to install?
For someone with basic mechanical skills, the installation is straightforward. The module is typically located on the right-hand firewall in the engine bay. It involves disconnecting the battery, unplugging the electrical connectors, and unbolting the old module to swap in the new one. Because it comes pre-programmed, no special tools are required for software setup.
Will I need to do anything after installation?
In some cases, a ‘crankshaft variation relearn’ or ‘security relearn’ procedure may be needed, which can often be done without special tools. We include instructions for these simple procedures to ensure a smooth process.
How do I provide my VIN?
After you complete your purchase, you can send us a message with your 17-digit VIN. We cannot ship your order until we receive this information, as it is essential for programming the module correctly for your specific truck.
Will this fit vehicles other than the 2006 Isuzu I-350?
Yes, this PCM, part number 12606373, is compatible with a wide range of 2004-2006 GM trucks and SUVs, including the Chevrolet Colorado, GMC Canyon, Hummer H3, and various Trailblazer/Envoy models. Please check the detailed fitment list on this page to confirm compatibility with your vehicle.