Programmed 2006 Isuzu I-280 PCM | Part #12606373 | Plug & Drive

Restore Your Isuzu’s Drivability!

Get your truck running like new with our pre-programmed Powertrain Control Module. We flash this PCM with the latest software using your vehicle’s VIN for a simple, direct-fit installation. Eliminate check engine lights and poor performance. Order today!

$184.95

+11.99 USPS Priority Shipping

Availability: In stock



Guaranteed Safe Checkout

Restore Your Truck’s Heartbeat and Drive with Confidence

Is your Isuzu I-280 acting erratically? Stalling, shifting poorly, or throwing confusing check engine lights? These are often the frustrating signs of a failing Powertrain Control Module (PCM), the electronic brain of your vehicle. Don’t let a faulty computer keep you off the road. This replacement PCM is the definitive solution, arriving at your doorstep pre-programmed to your truck’s exact Vehicle Identification Number (VIN). This means you can bypass expensive dealership programming and get back to a smooth, reliable drive faster than you thought possible.

Warning Signs Your PCM is Failing

A failing engine computer can manifest in numerous ways, often mimicking other component failures. If you’re experiencing any of the following, it’s time to consider the PCM as the root cause:

  • ✔ Unexplained Check Engine Light with codes like P0601, P0602, or P0606.
  • ✔ Rough or unpredictable idling.
  • ✔ A noticeable drop in fuel efficiency.
  • ✔ The engine cranks but refuses to start.
  • ✔ Harsh or erratic automatic transmission shifting.
  • ✔ Communication errors with diagnostic scan tools.

A Technician’s Note on Diagnosis

Before you replace the module, take a moment to perform a critical check. I’ve seen countless cases where a corroded battery terminal or a loose ground wire caused PCM-like symptoms. Ensure your battery connections are clean and tight, and verify the main engine-to-chassis ground strap is secure. This simple five-minute check can sometimes save you the cost of a replacement part. If those are solid, you can be confident the PCM is the issue.

Guided Installation to Restore Peace of Mind

Replacing the PCM on your Isuzu is a straightforward job you can tackle with basic hand tools. Our goal is to empower you to complete this repair with confidence. Follow these simple steps:

  1. Safety First: Begin by disconnecting the negative terminal from your vehicle’s battery. This prevents any electrical shorts during the installation process.
  2. Locate the Module: On your 2006 I-280, the PCM is located on the right-hand (passenger) side of the firewall in the engine bay.
  3. Disconnect and Remove: Carefully unplug the electrical connectors from the old PCM. They have locking tabs that need to be released. Once disconnected, unbolt the module from its mounting bracket.
  4. Install the New PCM: Mount your new, pre-programmed PCM onto the bracket and securely plug in the electrical connectors. You’ll hear a click as they lock into place.
  5. Reconnect and Start: Reconnect the negative battery terminal. The vehicle may need to complete a security relearn procedure, which typically involves turning the key to the ‘ON’ position for 10-15 minutes before starting. Your truck is now ready to run with its revitalized electronic brain!

Guaranteed Fitment for Your 2006 Isuzu I-280 PCM

This module is a direct-fit replacement, programmed specifically for your vehicle. It is also compatible with a wide range of other makes and models that share this platform. Please verify your vehicle is on the list below.

  • ✔ Chevrolet Colorado: 2004-2006
  • ✔ GMC Canyon: 2004-2006
  • ✔ Hummer H3: 2006
  • ✔ Isuzu I-280 / I-350: 2006
  • ✔ Buick Rainier: 2006 (4.2L)
  • ✔ Chevrolet Trailblazer / EXT: 2006 (4.2L)
  • ✔ GMC Envoy / XL: 2006 (4.2L)
  • ✔ Isuzu Ascender: 2006 (4.2L)
  • ✔ Saab 9-7X: 2006 (6 cylinder)

This unit replaces numerous original part numbers, including: 12569773, 12588650, 12589311, 12591647, 12594430, 12596783, 12597521, 12600818, 12604438, 12606373, and more.

Frequently Asked Questions

What is a PCM and what does it do?

The Powertrain Control Module (PCM) is the central computer that manages your vehicle’s engine and transmission. It controls critical functions like fuel injection, ignition timing, and shift points to ensure optimal performance, fuel economy, and emissions.

Is this part ready to install out of the box?

Yes! This is the key benefit. We program the module to the specific VIN you provide during checkout. This ensures it communicates perfectly with your truck’s other systems, making it a true plug-and-drive solution without needing a trip to the dealer.

How do I provide my VIN?

After you complete your purchase, you will receive instructions on how to send us your vehicle’s 17-digit VIN. We cannot ship your part until we receive this information, as the programming is essential for it to function correctly.

Where can I find my VIN?

Your VIN can be found on a metal plate on the driver’s side dashboard (visible through the windshield), on the driver’s side door jamb sticker, or on your vehicle’s registration and insurance documents.

Do I need to return my old PCM?

No core charge or return is required for this particular part. You can keep your old module or dispose of it responsibly.

Condition

Refurbished

Year

Genuine OEM

Yes

MPN

12606373

Brand

GM

Year

2006

Model

isuzu-i-280

Hardware Type

Interchange part number

Manufacturer Part Number

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