2006 Isuzu I-280 PCM 12593531 | Programmed to Your VIN

Restore Your Truck’s Performance

Get a reliable, plug-and-play Powertrain Control Module for your 2006 Isuzu I-280. Each unit is professionally programmed to your vehicle’s VIN with the latest GM software for a simple, no-hassle installation. Order today to get your truck running smoothly again!

$184.95

+11.99 USPS Priority Shipping

Availability: In stock



Guaranteed Safe Checkout

Restore Your Truck’s Brain and Bring Back Peak Performance

Is your 2006 Isuzu I-280 running rough, throwing confusing check engine lights, or refusing to start? A failing Powertrain Control Module (PCM) can feel like a mysterious and frustrating problem, turning your reliable truck into a source of daily stress. This isn’t just an inconvenience; it’s a matter of dependability. You need a solution that works right out of the box. This is the heart of your vehicle’s operation, and we provide a direct, pre-programmed replacement to restore its health and your peace of mind.

We take the guesswork out of the repair. Simply provide your vehicle’s VIN during checkout, and our technicians will flash this module with the latest, most stable software updates directly from GM. This ensures perfect communication between your engine, transmission, and other vital systems, just as the manufacturer intended. Get ready to experience a smoother idle, responsive acceleration, and the confident feeling of a truck that runs exactly as it should.

Warning Signs and How to Overcome Them

If your truck is exhibiting any of these symptoms, a faulty PCM could be the culprit. Replacing it can be the definitive solution to these headaches:

  • ✔ Unexplained Check Engine Light with codes like P0601, P0606, or communication errors.
  • ✔ Intermittent stalling or engine shutting off while driving.
  • ✔ Rough idling, misfires, or a noticeable drop in fuel economy.
  • ✔ Harsh or erratic automatic transmission shifting.
  • ✔ Complete no-start condition where the engine cranks but won’t fire up.
  • ✔ Failure to pass emissions testing due to module-related faults.

Guided Installation to Restore Your 2006 Isuzu I-280 PCM

This repair is more straightforward than you might think. With basic hand tools and a little patience, you can get your truck back on the road. Follow these steps for a confident installation:

  1. Safety First: Always disconnect the negative terminal from your vehicle’s battery and wait at least 15 minutes to allow the system to fully discharge.
  2. Locate the Module: On your 2006 Isuzu I-280, the PCM is typically mounted on the right-hand (passenger side) of the firewall in the engine bay.
  3. Disconnect and Remove: Carefully unplug the electrical connectors. They have locking tabs that need to be released. Once disconnected, unbolt the old module from its mounting bracket.
  4. Install the New PCM: Mount your new, pre-programmed PCM in the same location. Securely reconnect the electrical harnesses, ensuring they click into place.
  5. Reconnect Power: Reattach the negative battery terminal and tighten it securely.
  6. Perform Security Relearn: You will need to perform a simple key-cycle security relearn procedure. This typically involves turning the key to the ‘ON’ position for 10-15 minutes, then ‘OFF’ for 10 seconds, and repeating this two more times. This allows the new PCM to recognize your vehicle’s anti-theft system. Your truck should then start normally.

From the Garage: The Case of the Phantom Stall

We had a customer with a 2006 Chevy Colorado, a sibling to the I-280, who was at his wit’s end. His truck would randomly stall at stoplights, but never threw a consistent code. He’d replaced sensors and checked wiring for weeks. The final diagnosis pointed to a failing PCM that was overheating intermittently. We sent him a VIN-programmed unit, he installed it in his driveway in under an hour, and the problem vanished. He called us a week later just to say how great it felt to trust his truck again on his daily commute. That’s the confidence we aim to deliver.

Tailored Fit for Your Ride

This module is a direct replacement for a wide range of GM vehicles, ensuring a perfect fit and function. It is compatible with the following part numbers: 12569773, 12588650, 12589311, 12589585, 12591647, 12591648, 12593531, 12593532, 12594430, 12594431, 12596783, 12596784, 12597521, 12597776, 12597777, 12600818, 12604438, 12604439, 12606369, 12606373, 12606374, 12606398, 12606399, 19209820, 19209821.

This part will fit these makes and models with these options:

  • COLORADO 04-06 Electronic Control Module; (RH firewall)
  • CANYON 04-06 Electronic Control Module; (RH firewall)
  • ENVOY 06 Electronic Control Module; 4.2L (LH engine)
  • ENVOY XL 06 Electronic Control Module; (LH engine), 4.2L
  • HUMMER H3 06 Electronic Control Module; (RH firewall)
  • ISUZU ASCENDER 06 Electronic Control Module; 4.2L (LH engine)
  • ISUZU I-280 06 Electronic Control Module; (RH firewall)
  • ISUZU I-350 06 Electronic Control Module; (RH firewall)
  • RAINIER 06 Electronic Control Module; (LH engine), 4.2L
  • SAAB 9-7X 06 Electronic Control Module; (LH engine), 6 cylinder
  • TRAILBLAZER 06 Electronic Control Module; (LH engine), 4.2L
  • TRAILBLAZER EXT 06 Electronic Control Module; (LH engine), 4.2L

Frequently Asked Questions

What does ‘programmed to my VIN’ actually mean?

It means we load your vehicle’s unique Vehicle Identification Number (VIN) and the latest GM-certified software onto the module before shipping. This ensures the PCM has the correct engine and transmission calibrations, anti-theft information, and other settings specific to your truck, making installation much simpler.

Will I need to do any additional programming after I install it?

No expensive dealer programming is needed. The only step required after installation is a simple security relearn procedure, which you can do yourself with just the ignition key. We include instructions for this easy process.

Where is the PCM located on my 2006 Isuzu I-280?

The Powertrain Control Module is located in the engine compartment, mounted to the firewall on the passenger side of the vehicle.

Will this fix my check engine light?

If the check engine light is caused by a faulty PCM or related internal processor errors (like code P0601), this replacement module will solve the problem. However, if the light is on due to a bad sensor or other mechanical issue, that part will still need to be addressed.

Is this a simple plug-and-play installation?

Yes, for the most part. Once you perform the quick security relearn procedure after the physical installation, the module is ready to go. The programming to your VIN is done beforehand to make the process as seamless as possible for you.

Condition

Refurbished

Year

Genuine OEM

Yes

MPN

12593531

Brand

GM

Year

2006

Model

isuzu-i-280

Hardware Type

Interchange part number

Manufacturer Part Number

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