Restore Peak Performance to Your 1999-2001 GMC Safari
Is your trusty GMC Safari or GM truck suddenly running rough, stalling, or throwing a stubborn Check Engine Light? As an automotive diagnostician with over two decades of experience, I’ve seen these symptoms countless times. Often, the root cause isn’t a faulty sensor or a bad wire; it’s the vehicle’s brain—the Powertrain Control Module (PCM). This isn’t just another part; it’s the central command unit for your engine and transmission. When it fails, it can create a cascade of frustrating and hard-to-diagnose problems.
We offer a straightforward, reliable solution: a high-quality replacement 1999-2001 GMC Safari PCM that comes fully programmed to your vehicle’s specific Vehicle Identification Number (VIN). This isn’t a blank module that leaves you stranded, needing an expensive trip to the dealership for programming. We handle the critical software flashing for you, loading the latest GM updates before it even ships. This ensures a seamless installation process, getting you or your customer back on the road with confidence.
A Technician’s Notebook: The Phantom Misfire
I once had a 2000 Chevy Astro van (which uses the same platform as the Safari) in my bay with a persistent, random misfire code that no one could solve. The owner had already replaced the plugs, wires, cap, and rotor twice. We checked fuel pressure, tested the injectors, and scoped the ignition system—everything looked perfect. The misfire was intermittent and maddening. On a hunch, I checked the PCM’s driver circuits. I found that the injector driver for cylinder 3 was intermittently failing internally—a classic sign of PCM degradation. We swapped in a VIN-programmed module like this one, and the van ran like it just rolled off the factory floor. It’s a powerful reminder that the control unit itself can be the hidden culprit.
Is Your GM Vehicle Showing These Symptoms?
- ✔ Persistent Check Engine Light with codes like P0601 (Internal Control Module Memory Check Sum Error) or P0606 (ECM/PCM Processor Fault).
- ✔ Unexplained drop in fuel economy.
- ✔ Engine stalling, stumbling, or hesitating during acceleration.
- ✔ Harsh or erratic automatic transmission shifting.
- ✔ Complete no-start condition where the engine cranks but won’t fire up.
- ✔ Failure to communicate with a diagnostic scan tool.
A Straightforward Guide to Your PCM Swap
Replacing the PCM on these vehicles is a job most DIYers can handle in their own driveway. Our VIN programming makes it a true plug-and-play process.
- Safety First: Always disconnect the negative terminal from your vehicle’s battery and secure it away from the post.
- Locate the PCM: On the GMC Safari and Chevy Astro, the PCM is typically found on the driver’s side of the engine compartment, near or under the battery tray. On pickups and other vans, it’s often on the driver’s side fender wall.
- Disconnect the Harnesses: Carefully unclip and remove the electrical connectors from the old module. These connectors are color-coded and keyed, so they can only go back on one way.
- Remove the Old Module: Unbolt the old PCM from its mounting bracket. Keep the hardware as you will reuse it.
- Install the New Module: Mount your new, pre-programmed PCM onto the bracket and securely fasten the bolts.
- Reconnect Everything: Firmly plug the electrical harnesses back into the new module until they click. Reconnect your negative battery terminal.
- Final Step: Start the engine and let it idle for a few minutes to allow the computer to complete its internal checks. A short test drive will help it finalize its learning process.
Verified Vehicle Compatibility
This module is a direct replacement for part numbers 16263494, 16265035, 8162634940, and 218-11787. Please verify your part number or use the fitment guide below. Providing your VIN at checkout is essential for us to ensure perfect programming and compatibility for your specific vehicle.
CHEVROLET 2500 PICKUP 00 Electronic Control Module; gasoline (LH front engine compartment)
EXPRESS 1500 VAN 00 Electronic Control Module; (LH rear engine compartment)
EXPRESS 2500 VAN 00 Electronic Control Module; (LH rear engine compartment), gasoline
EXPRESS 3500 VAN 00 Electronic Control Module; (LH rear engine compartment), gasoline
SAVANA 1500 VAN 01-02 Electronic Control Module; (LH rear engine compartment), ID 16263494
ASTRO 00-01 Electronic Control Module; (LH front by battery), ID 16263494
GMC 3500 PICKUP 00 Electronic Control Module; gasoline (LH front engine compartment)
EXPRESS 2500 VAN 01-02 Electronic Control Module; (LH rear engine compartment), gasoline, ID 16263494
S10/S15/SONOMA 99-00 Electronic Control Module; (RH front engine compartment), 4.3L
SAVANA 1500 VAN 00 Electronic Control Module; (LH rear engine compartment)
ASTRO 99 Electronic Control Module; (LH front by battery), (4.3L), ID 16263494
ISUZU HOMBRE 99-00 Electronic Control Module; (RH front engine compartment), 4.3L (6 cylinder)
SAFARI (GMC) 99-01 Electronic Control Module; (LH front by battery), ID 16263494
SAVANA 3500 VAN 01-02 Electronic Control Module; (LH rear engine compartment), gasoline, ID 16263494
EXPRESS 1500 VAN 99 Electronic Control Module; (LH rear engine compartment), ID 16263494
TAHOE 00 Electronic Control Module; Classic style (LH front engine compartment)
YUKON 99 Electronic Control Module; (LH engine compartment), ID 16263494
ESCALADE 99-00, YUKON DENALI 00, And many more GM Trucks, Vans, and SUVs.
Frequently Asked Questions
What is VIN programming and why is it important?
VIN programming is the process of loading your vehicle’s specific software and settings into the PCM. This includes information about your engine, transmission, and factory options. Without it, the module won’t communicate correctly with your vehicle, leading to running issues or a no-start condition. We do this for you so it’s ready for installation.
Do I need to perform a security or CASE relearn after installation?
For most vehicles on this list, our programming makes this a plug-and-play part. However, some GM vehicles with advanced anti-theft systems (Passlock/VATS) may require a simple, 30-minute key-cycle relearn procedure. Instructions are included if necessary for your specific vehicle. No special tools are needed.
Where is the PCM located on my 1999 GMC Safari?
On the 1999-2001 GMC Safari and its sibling, the Chevy Astro, the Powertrain Control Module is located in the engine bay on the driver’s side, typically mounted below the battery tray.
How do I send you my VIN?
After you complete your purchase, you will receive instructions on how to reply with your 17-digit VIN. You can typically find your VIN on your vehicle’s registration, insurance card, or on a plate on the driver’s side dashboard visible through the windshield.
Will this fix my check engine light?
If the check engine light is caused by an internal failure of the PCM (like with code P0601), then yes, this module will resolve the issue. However, if the light is on due to a separate faulty sensor or component, that part will still need to be addressed.