Programmed 2016 Express 2500 Van ECM 12643636 | Engine Control Module

Get Your Work Van Running Right

Stop letting a faulty engine computer keep your 2016 Express 2500 Van off the road. This direct-fit Engine Control Module (ECM) arrives programmed to your specific VIN with the latest GM software. It’s the definitive fix for stalling, no-start conditions, and persistent check engine lights, saving you a trip to the dealer. Get back to work faster—order today!

$225.95

+11.99 USPS Priority Shipping

Availability: In stock



SKU: 590-02768-6 Categories: ,
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Restore Your Van’s Performance with a VIN-Programmed ECM

Is your 2016 Chevrolet Express 2500 Van suddenly unreliable? If you’re dealing with a persistent check engine light, erratic engine behavior, stalling, or a frustrating no-start condition, a failing Engine Control Module (ECM) is a very likely culprit. For a work vehicle, downtime isn’t just an inconvenience—it’s lost income. This direct-fit ECM, part number 12643636, is the solution to get your van back in service quickly and reliably, without the high costs and long waits at the dealership.

As a technician with over two decades of experience, I’ve seen firsthand how a faulty ECM can cause a cascade of confusing problems that are difficult to diagnose. This isn’t just a part; it’s the brain of your vehicle’s engine management system. We take the guesswork and hassle out of the replacement process. Simply provide your van’s Vehicle Identification Number (VIN) during checkout, and our specialists will flash this module with the latest, most stable GM software updates specific to your vehicle. It arrives at your door ready for installation, eliminating the need for expensive scan tools or a trip to the dealer for programming.

Is Your Express Van Showing These Symptoms?

  • ✔ Check Engine Light is on with communication codes (like U0100) or internal processor failure codes (P0601, P0606).
  • ✔ The engine cranks but refuses to start.
  • ✔ Unexplained stalling, especially when coming to a stop or at idle.
  • ✔ Noticeable decrease in fuel economy and poor engine performance.
  • ✔ Harsh or erratic automatic transmission shifting.
  • ✔ Failure to pass state emissions testing.
  • ✔ Other modules on the vehicle are not communicating with the ECM.

A Technician’s Notebook

I remember a 2016 Express 2500 from a local plumbing company that came into the bay. The complaint was intermittent stalling and a no-start that would happen without warning, usually on the hottest days. They had already replaced the fuel pump and crank sensor at another shop, but the problem persisted. After hooking up my diagnostic scanner, I noticed the live data stream from the ECM would freeze just before the engine quit. There were no hard codes, just a history of network communication faults. This pointed to an internal ECM failure under thermal stress. We installed one of these VIN-programmed modules, performed the security relearn, and the van was back on the road reliably the same afternoon. It’s a classic case where chasing parts gets expensive, but correctly identifying the faulty computer provides the definitive fix.

A Straightforward Guide to Installation

  1. ✔ Safety First: Always disconnect the negative terminal from your vehicle’s battery and wait at least 15 minutes for the system capacitors to discharge.
  2. ✔ Locate the ECM: On the 2016 Express Van, the ECM is typically found in the left-hand (driver’s side) rear of the engine compartment.
  3. ✔ Disconnect and Remove: Carefully unplug the electrical connectors. They have locking tabs that must be released. Once disconnected, unbolt the module from its mounting bracket.
  4. ✔ Install the New Module: Bolt the new, pre-programmed ECM into place. Securely reconnect the electrical harnesses, ensuring the locking tabs click into place.
  5. ✔ Reconnect Battery: Reattach the negative battery terminal.
  6. ✔ Perform Security Relearn: You will likely need to perform a security relearn procedure (often called a Passlock or Passkey relearn). This typically involves turning the key to the ‘ON’ position for 10-15 minutes, then off, and repeating two more times. This allows the vehicle’s anti-theft system to recognize the new ECM. Your van will not start until this is completed.

Verified Vehicle Compatibility

This ECM is a direct replacement for part number 12643636 and is interchangeable with part numbers 12668866, 12668994, 12663405, 12670335, 22819494, and 12692200. It fits a wide range of GM vehicles, including:

  • Chevrolet Express 2500/3500 Van (2016): 4.8L & 6.0L Engines
  • GMC Savana 2500/3500 Van (2016): 4.8L & 6.0L Engines
  • Chevrolet Silverado 2500/3500 Pickup (2012-2016): 6.0L Engine
  • GMC Sierra 2500/3500 Pickup (2012-2016): 6.0L Engine
  • Chevrolet Cruze (2012-2016)
  • Chevrolet Sonic (2012-2016)
  • Chevrolet Trax (2013-2016)
  • Chevrolet Volt (2011-2015)
  • Chevrolet Spark (2014-2015)
  • Buick Encore (2013-2016)
  • Cadillac ELR (2014-2016)
  • And more. Always verify your part number or contact us with your VIN to confirm fitment.

Frequently Asked Questions

How does the VIN programming work?

After you complete your purchase, you will need to provide us with your vehicle’s 17-digit VIN. Our technicians use this number to access the official GM database and load the correct software and calibrations for your specific vehicle configuration. This ensures perfect compatibility and performance right out of the box.

Is this a simple plug-and-play installation?

Yes, for the most part. The module is programmed to your VIN, making the software side plug-and-play. However, as with nearly all modern GM ECM replacements, you must perform a security relearn procedure after installation. This is a simple process that pairs the new module to your vehicle’s anti-theft system and does not require any special tools. Instructions are readily available online or in service manuals.

Will this fix my specific problem?

This module will correct issues directly caused by a failing ECM, such as internal processor faults (P06xx codes), communication errors, and erratic behavior tied to the computer itself. While it solves many common problems, it’s essential to ensure your vehicle has been properly diagnosed. This part will not fix issues caused by faulty sensors, wiring, or other mechanical components.

Do I need to send my old ECM back?

No core charge or return is required for this part. You can keep your old module or dispose of it responsibly.

What if my part number is slightly different?

This ECM replaces several GM part numbers, including 12668866, 12668994, and others listed in the description. As long as your original part number is on our cross-reference list, this module will function correctly once programmed to your VIN.

Condition

Refurbished

Year
Genuine OEM

Yes

MPN

12643636

Interchange part number

PartNumber

590

Model

EXPRESS 2500 VAN

Year

2012

Brand

GM

Manufacturer Part Number

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