Programmed 2006 TrailBlazer PCM 12597521 | ECM for 4.2L | VIN Flashed

End Your TrailBlazer’s Running Issues.

Tired of check engine lights, stalling, or no-start problems? This Powertrain Control Module is the definitive fix. It arrives pre-programmed to your vehicle’s VIN with the latest GM software, eliminating the need for a costly dealership visit. It’s a direct-fit, easy-to-install solution to restore your truck’s performance and reliability. Get back on the road with confidence—order yours today!

$184.95

+11.99 USPS Priority Shipping

Availability: In stock



SKU: 590-00320-27 Categories: ,
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Restore Peak Performance to Your GM Truck or SUV

Is your 2006 TrailBlazer, Envoy, or other compatible GM vehicle acting up? If you’re dealing with a persistent check engine light, erratic engine behavior, or frustrating no-start conditions, a failing Powertrain Control Module (PCM) is often the culprit. As the central computer for your engine and transmission, its health is critical. This isn’t just a replacement part; it’s a direct-fit solution to restore your vehicle’s reliability and drivability. We take the guesswork and hassle out of the repair by programming this module specifically to your vehicle’s VIN with the latest factory software updates from GM.

Is Your Truck Showing These Signs of PCM Failure?

A faulty PCM can cause a wide range of symptoms that can be easily misdiagnosed. Over my 20 years in the shop, I’ve seen these modules cause some of the most confusing issues. Before you start replacing sensors, check if you’re experiencing any of the following:

  • âś” Unexplained Check Engine Light (CEL) with codes like P0601, P0605, or P0606 (Internal Control Module errors).
  • âś” Engine stalling, stumbling, or running rough for no apparent reason.
  • âś” Complete no-start condition where the engine cranks but won’t fire up.
  • âś” Poor fuel economy and a noticeable loss of power.
  • âś” Harsh or incorrect transmission shifting.
  • âś” Communication errors with your scan tool (e.g., U0100).

Case Study: A Tricky Diagnosis

A customer brought in a 2006 TrailBlazer with an intermittent no-start that was driving him crazy. It would be fine for weeks, then refuse to start, only to fire up an hour later. No consistent codes were stored. After checking all the basics—battery, starter, fuel pressure—we focused on the PCM. On these GMT360 platform vehicles, the PCM is mounted on the driver’s side of the engine block. After years of heat cycles, the internal solder joints and processors can become sensitive. We used a heat gun to gently warm the PCM, and sure enough, the no-start condition returned every time. A new, properly programmed PCM fixed it for good. This is a classic failure I’ve seen dozens of times.

The Smart Solution: Pre-Programmed for Your Vehicle

The biggest hurdle in replacing a modern vehicle computer is the programming. Traditionally, this required towing your vehicle to a dealership and paying hefty labor fees. We eliminate that step entirely. By providing us with your VIN during checkout, you receive a 2006 TrailBlazer PCM that is 100% ready for installation. It arrives flashed with the most current GM software, ensuring all factory improvements for performance and efficiency are applied. This is the most effective way to ensure a successful, long-lasting repair.

A Straightforward Guide to Installation

Replacing the PCM on these vehicles is a job most DIYers can handle with basic hand tools. Follow these steps carefully for a smooth installation.

  1. Safety First: Always disconnect the negative terminal from your vehicle’s battery and secure it away from the post to prevent any accidental reconnection.
  2. Locate the PCM: On most 4.2L models like the TrailBlazer and Envoy, the PCM is mounted on the driver’s side of the engine block, below the intake manifold. On Colorado, Canyon, and H3 models, it’s typically on the passenger-side firewall.
  3. Disconnect the Connectors: The PCM will have several large electrical connectors. Each has a locking tab or lever. Carefully release the locks and gently pull the connectors straight out. Never force them. Inspect the pins for any corrosion or damage.
  4. Remove the Old Module: The PCM is held in place by a few bolts or nuts. Remove them and carefully slide the old module out of its mounting bracket.
  5. Install the New Module: Seat your new, pre-programmed PCM into the bracket and secure it with the mounting bolts. Do not overtighten.
  6. Reconnect Everything: Firmly plug the electrical connectors back into the new PCM until they click into place. Reconnect your negative battery terminal.
  7. Perform Security Relearn: In most cases, you will need to perform a simple security relearn procedure to sync the new PCM with your vehicle’s anti-theft system. This usually takes 10-30 minutes and requires only your ignition key. We include instructions for this process.

Verified Vehicle Compatibility

This module is a direct replacement for a wide range of GM vehicles and interchanges with numerous part numbers, including 12597521. Please verify your vehicle is on this list:

  • Buick Rainier: 2006 (4.2L)
  • Chevrolet Colorado: 2004-2006
  • Chevrolet TrailBlazer & TrailBlazer EXT: 2006 (4.2L)
  • GMC Canyon: 2004-2006
  • GMC Envoy & Envoy XL: 2006 (4.2L)
  • Hummer H3: 2006
  • Isuzu Ascender: 2006 (4.2L)
  • Isuzu i-280 / i-350: 2006
  • Saab 9-7x: 2006 (6-Cylinder)

Frequently Asked Questions

What is a security relearn procedure?

It’s a simple process that syncs the new PCM to your vehicle’s anti-theft system so the engine will start. It typically involves turning the key to the ‘ON’ position for 10 minutes, then ‘OFF’, and repeating this sequence three times. We provide clear instructions.

Do I need to send my old PCM (core) back?

This purchase does not require a core return. You can keep your old part.

Where do I find my VIN?

Your 17-digit Vehicle Identification Number (VIN) can be found on your driver’s side dashboard (viewable through the windshield), on the driver’s side door jamb sticker, or on your vehicle’s registration and insurance documents.

Is this PCM new or used?

This is a high-quality, tested, and guaranteed functional part. It is programmed with the latest GM software to ensure reliability and performance that meets or exceeds the original factory specifications.

Will this fix my specific problem?

This module will correct issues directly caused by a faulty PCM. While it resolves the most common symptoms, we always recommend a proper diagnosis by a qualified mechanic to confirm the PCM is the point of failure before ordering.

Condition

Refurbished

Genuine OEM

Yes

MPN

12597521

Brand

GM

Year

2006

Model

TRAILBLAZER EXT

Hardware Type

Interchange part number

Manufacturer Part Number

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