Programmed 1999-2001 GMC Safari PCM 16265035 | Engine Control Module

End Your Van’s Engine Troubles.

Get your 1999-2001 GMC Safari running right again with this fully programmed Powertrain Control Module (PCM). It arrives flashed to your vehicle’s VIN with the latest GM software, eliminating the need for a dealer visit. This is a direct-fit solution for fixing check engine lights, poor performance, and erratic shifting. Restore reliability and drive with confidence. Order now for a simple, plug-in fix!

$114.95

+11.99 USPS Priority Shipping

Availability: In stock



SKU: 590-05454-55 Categories: ,
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Restore Peak Performance to Your GMC Safari with a VIN-Programmed PCM

If you’re dealing with a frustrating Check Engine Light, erratic engine behavior, or transmission shifting problems in your 1999-2001 GMC Safari, a failing Powertrain Control Module (PCM) is often the culprit. As the central computer of your vehicle, the PCM controls everything from fuel mixture and ignition timing to transmission shift points. When it starts to fail, it can cause a cascade of issues that are difficult to diagnose. This module is the direct, reliable solution to get your van running smoothly again.

We take the guesswork and hassle out of the repair. Unlike sourcing a part from a junkyard or a generic retailer, we program this module specifically for your vehicle using your VIN. This means it arrives loaded with the latest GM software updates, ensuring optimal performance and compatibility right out of the box. You get a component that is ready for installation, saving you a costly trip to the dealership for programming.

A Technician’s Notebook

I recently had a 2000 Chevy Astro in the shop—mechanically identical to the Safari—with a complaint of intermittent stalling at stoplights and a harsh 1-2 shift. The owner had already replaced the fuel filter and spark plugs with no luck. No hard codes were stored, just a pending P0300 (Random Misfire). After checking fuel pressure and finding no vacuum leaks, I focused on the PCM. On these vans, the PCM is located right by the battery, where it’s exposed to heat cycles and potential acid fumes. We swapped in a VIN-programmed module, and the difference was immediate. The idle smoothed out, the transmission shifted like new, and the stalling issue was completely gone. It’s a classic failure I’ve seen dozens of times on these 4.3L platforms.

Is Your GMC Van Showing These Signs?

A faulty engine computer can manifest in several ways. If you’re experiencing any of the following, this module is your likely solution:

  • ✔ Persistent Check Engine Light (CEL)
  • ✔ Stored diagnostic trouble codes (DTCs) like P0601 (Internal Control Module Memory Check Sum Error) or P0606 (ECM/PCM Processor Fault)
  • ✔ Engine stalling, stumbling, or rough idling
  • ✔ Poor fuel economy
  • ✔ Harsh or erratic automatic transmission shifting
  • ✔ Failure to pass an emissions test
  • ✔ Complete no-start condition where the engine cranks but won’t fire

A Straightforward Guide to Installation

Installing your new 1999-2001 GMC Safari PCM is a job most DIYers can handle in under an hour. Following these steps will ensure a smooth process.

  1. Safety First: Always disconnect the negative terminal from your vehicle’s battery and secure it away from the post to prevent any accidental reconnection.
  2. Locate the PCM: On the GMC Safari and Chevy Astro, the PCM is located in the engine compartment on the driver’s side, typically on a bracket near or under the battery.
  3. Disconnect Connectors: Carefully unclip and remove the electrical harness connectors from the old module. These connectors have locking tabs that need to be released before pulling. Avoid forcing them.
  4. Remove the Old Module: Unbolt the old PCM from its mounting bracket. Keep the hardware, as you may need to reuse it for the new module.
  5. Install the New Module: Mount your new, pre-programmed PCM onto the bracket and securely fasten it. Reconnect the electrical harnesses, making sure they click firmly into place.
  6. Reconnect Battery: Reattach the negative battery terminal and tighten it securely.
  7. Perform Security Relearn (If Needed): In many cases, you may need to perform a simple security relearn procedure. This typically involves turning the key to the ‘ON’ position for 10-15 minutes, then ‘OFF’ for 10 seconds, and repeating this cycle three times. This allows the new PCM to synchronize with your vehicle’s anti-theft system. Your vehicle will likely not start until this is completed.

Verified Compatibility for Your GM Vehicle

This Powertrain Control Module is a direct replacement for service number 16265035 and is also compatible with part numbers 16263494, 8162634940, 218-11787, and 21811787. It fits a wide range of GM trucks and vans. Please verify your vehicle is on the list below. Note: Some models require matching the ID number 16263494.

This module fits various 1998-2002 GM models including:

  • GMC Safari / Chevrolet Astro (1999-2001)
  • GMC Savana / Chevrolet Express Vans (1500, 2500, 3500) (1999-2002)
  • GMC Sierra / Chevrolet Silverado Pickups (1500, 2500, 3500) (1999-2000)
  • GMC Yukon / Chevrolet Tahoe / Cadillac Escalade (1999-2000)
  • GMC Jimmy / Chevrolet Blazer / Oldsmobile Bravada / GMC Envoy (1998-2000)
  • GMC Sonoma / Chevrolet S10 / Isuzu Hombre (1998-2000)

After you place your order, you will need to provide us with your vehicle’s 17-digit VIN. Our technicians use this number to load the exact, correct software and calibrations from GM for your specific vehicle configuration. This ensures the module works perfectly upon installation.

No special tools are required. Basic hand tools like a socket set and ratchet are typically all you need to disconnect the battery and unbolt the module from its bracket. The entire process is designed to be straightforward for a DIY mechanic.

In many cases, yes. The PCM controls transmission line pressure and shift solenoids. A failing PCM is a very common cause of harsh shifting, delayed engagement, or getting stuck in a gear on these GM vehicles. If the transmission itself is mechanically sound, this module can resolve those electronic control issues.

This module will resolve any issues directly caused by a faulty PCM, including internal processor faults (like code P0601). If your check engine light is on due to a different failed component (like an oxygen sensor or EGR valve), you will still need to address that separate issue. However, replacing a known-bad PCM is a critical first step.

The security relearn, or Passlock relearn, syncs the new PCM to your vehicle’s anti-theft system. A common method is the ’30-minute relearn’: turn the key to ON (don’t start), wait until the security light goes out (about 10 mins), turn key OFF for 10 seconds. Repeat this two more times for a total of three cycles. The vehicle should then start.

Condition

Refurbished

Year
Genuine OEM

Yes

MPN

16265035

Interchange part number

Model

safari-gmc

Year

1999

Brand

GM

Manufacturer Part Number

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