Programmed 1999-2000 GMC 2500 PCM 16265035 | VIN Matched Powertrain Module

End Your Truck’s Running Problems.

Get a reliable replacement Powertrain Control Module for your 1999-2000 GMC 2500, delivered to you fully programmed for your specific VIN. This is the direct-fit solution for fixing check engine lights, stalling, and poor performance without a trip to the dealer. Restore your truck’s reliability and drivability with a part that’s ready to install right out of the box. Order today to get your truck back on the road fast!

$114.95

+11.99 USPS Priority Shipping

Availability: In stock



SKU: 590-05454-38 Categories: ,
Guaranteed Safe Checkout

Restore Your Truck’s Brain and Get Back on the Road

There’s nothing more frustrating than a reliable truck that suddenly starts acting up. Whether you’re dealing with a persistent Check Engine Light, unpredictable stalling, or a complete no-start situation, the problem often points to a failing Powertrain Control Module (PCM). As the central computer of your vehicle, the PCM controls everything from fuel mixture and ignition timing to transmission shifting. When it fails, your truck’s performance and reliability suffer. This replacement PCM is the definitive solution, arriving at your door programmed with the latest GM software updates, specifically matched to your vehicle’s VIN.

A Technician’s Notebook

I remember a 1999 Chevy Silverado 2500 that came into my bay with a ghost of a problem. The owner had been to three other shops for an intermittent stalling issue that left no codes behind. It would run fine for days, then die at a stoplight without warning. We checked fuel pressure, ignition components, and sensors—all tested fine. On a hunch, I monitored the PCM’s data stream during a long test drive. Right before it stalled, I saw the 5-volt reference signal flicker. That’s a classic sign of an internal PCM short. After replacing it with a VIN-programmed module like this one, the truck never stalled again. It’s a reminder that sometimes, the most confusing problems have a straightforward solution if you target the vehicle’s brain.

Is Your Truck’s Computer Showing These Signs?

A faulty PCM can cause a wide range of symptoms. If you’re experiencing any of the following, this module is likely the solution you need. In my 20+ years of experience, these are the most common indicators of a failing computer in these GM trucks and vans.

  • ✔ Persistent Check Engine Light with codes like P0601 (Internal Control Module Memory Check Sum Error) or P0606 (ECM/PCM Processor Fault).
  • ✔ Engine stalling, stumbling, or running rough for no apparent reason.
  • ✔ Vehicle refuses to start or has a hard time starting, even with a good battery and starter.
  • ✔ Noticeably poor fuel economy and loss of power.
  • ✔ Harsh or erratic automatic transmission shifting.
  • ✔ Failure to pass state emissions testing.

DIY-Friendly Installation: A Straightforward Guide

You don’t need to be a master mechanic to install this part. Our VIN programming service makes this a true plug-and-play repair, saving you a costly trip to the dealership. Just follow these simple steps to get your 1999-2000 GMC 2500 PCM installed.

  1. Safety First: Always disconnect the negative terminal from your vehicle’s battery before beginning any electrical work.
  2. Locate the Old PCM: On most of these trucks, the PCM is located in the engine compartment on the driver’s side, often near the battery or firewall. It’s a silver metal box with several large electrical connectors.
  3. Disconnect and Remove: Carefully unclip and remove all electrical connectors from the old module. Then, unbolt the module from its mounting bracket and remove it from the vehicle.
  4. Install the New Module: Bolt your new, pre-programmed PCM into the mounting bracket. Firmly reconnect all electrical connectors, ensuring they click securely into place.
  5. Reconnect and Start: Reconnect the negative battery terminal. The vehicle may require a security relearn or a Crankshaft Position Sensor (CASE) relearn, which can often be done with a capable scan tool or by following a specific drive cycle.

Verified Vehicle Compatibility

This module, service number 16265035, is a direct replacement for a wide range of GM vehicles. It is also compatible with part numbers 16263494, 8162634940, 218-11787, and 21811787. Please confirm your vehicle is on this list before ordering. Providing your VIN at checkout ensures we send you a perfectly matched and updated module.

CHEVROLET 1500 PICKUP 99 (5.0L/5.7L, ID 16263494)
CHEVROLET 2500 PICKUP 99-00 (Gasoline, ID 16263494 for ’99)
CHEVROLET 3500 PICKUP 99-00 (Gasoline, ID 16263494 for ’99)
SILVERADO 1500 PICKUP 99-00 (4.3L 6-Cyl)
TAHOE 99-00 (Gasoline, ’00 Classic Style)
SUBURBAN 1500/2500 99 (Gasoline, ID 16263494)
S10/S15/SONOMA 98-00 (4.3L)
BLAZER/JIMMY S15 98-00
ASTRO 99-01 (ID 16263494)
EXPRESS/SAVANA 1500/2500/3500 99-02 (Gasoline, check ID)
GMC 1500 PICKUP 99 (5.0L/5.7L, ID 16263494)
GMC 2500 PICKUP 99-00 (Gasoline, ID 16263494 for ’99)
GMC 3500 PICKUP 99-00 (Gasoline, ID 16263494 for ’99)
SIERRA 1500 PICKUP 99-00 (4.3L 6-Cyl)
YUKON 99-00 (Incl. Denali)
SAFARI (GMC) 99-01 (ID 16263494)
BRAVADA 98-00
ENVOY 98-00
ESCALADE 99-00
ISUZU HOMBRE 98-00 (4.3L)
Why do you need my VIN?
Your Vehicle Identification Number (VIN) allows us to program the PCM with the exact factory software and calibrations for your truck’s specific engine, transmission, and options. This ensures seamless communication between all modules and restores original performance and functionality.
Is any additional programming required after installation?
In most cases, no. Our service covers the main programming. However, some GM vehicles may require a quick security relearn procedure or a Crankshaft Variation (CASE) relearn. These can often be performed with a capable bi-directional scan tool or by a local mechanic.
Will this fix my transmission shifting problems?
If the shifting problems are caused by faulty electronic signals from a failing PCM, then yes, this part will resolve them. The PCM controls transmission line pressure and shift points, so a healthy module is critical for smooth operation.
How is this different from a generic part from a big box store?
Unlike off-the-shelf modules that arrive blank and require expensive dealer programming, our PCM is a complete solution. We handle the complex programming for you, making this a cost-effective and convenient repair that gets your truck fixed faster.
Condition

Refurbished

Year
Genuine OEM

Yes

MPN

16265035

Interchange part number

Model

gmc-2500-pickup

Year

1999

Brand

GM

Manufacturer Part Number

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