Restore Your GM Truck’s Brain and Get Back on the Road
As a technician with over two decades of experience under the hood, I’ve seen firsthand how a failing Powertrain Control Module (PCM) can turn a reliable truck into a source of constant frustration. If your 1999-2000 Cadillac Escalade, or another compatible GM vehicle, is suffering from bizarre electrical gremlins, poor performance, or won’t start at all, you’ve likely pinpointed the culprit. This isn’t just a replacement part; it’s a direct solution to restore your vehicle’s core operational integrity.
This module, part number 16265035, is the central command center for your engine and transmission. It controls everything from fuel mixture and spark timing to transmission shift points. When it fails, the symptoms can be confusing and widespread. That’s why we take the guesswork out of the repair. We flash this module with the latest GM-certified software specifically for your vehicle using the VIN you provide. This means it arrives at your door ready for installation, no expensive dealership programming required.
A Technician’s Notebook: The Intermittent Stall Case
I remember a 2000 Yukon Denali—which shares its platform with the Escalade—that came into my bay with a maddening problem: it would randomly stall at traffic lights, but only when warm. No check engine light, no consistent codes. We checked fuel pressure, sensors, and wiring for days. On a hunch, I monitored the PCM’s internal temperature data and saw it spike just before a stall. The processor was failing under heat soak. We swapped in a VIN-programmed PCM like this one, and the problem was solved instantly. It’s often these internal, invisible failures that cause the biggest headaches, and a quality replacement is the only true fix.
Is Your Truck or Van Showing These Signs of PCM Failure?
- ✔ Check Engine Light is on with communication-related or internal processor codes (e.g., P0601, P0605, P0606).
- ✔ The engine cranks but refuses to start.
- ✔ Unexplained drops in fuel economy.
- ✔ Rough or erratic idling and stalling.
- ✔ Harsh or incorrect automatic transmission shifting.
- ✔ Failure to pass an emissions test.
- ✔ Other modules on the vehicle are not communicating with the PCM.
A Straightforward Guide to Installation
Replacing your 1999-2000 Escalade PCM is a job most DIYers can handle in their own driveway. Since we’ve handled the programming, it’s a true plug-and-play process.
- Safety First: Always disconnect the negative terminal from your vehicle’s battery and secure it away from the post to prevent accidental reconnection.
- Locate the PCM: On most compatible trucks and SUVs like the Escalade, Tahoe, and pickups, the PCM is located in the engine bay, typically on the driver’s side fender well or under the battery tray. On Express and Savana vans, it’s often found in the LH rear of the engine compartment.
- Disconnect and Remove: Carefully unplug the wiring harness connectors. They have locking tabs that may need to be gently pried or squeezed. Once disconnected, unbolt the module from its mounting bracket.
- Install the New Module: Bolt your new, pre-programmed PCM into place. Reconnect the wiring harnesses, ensuring they click securely into place. Double-check that the connections are clean and free of corrosion.
- Reconnect and Start: Reattach the negative battery terminal. In some cases, a security relearn procedure may be necessary, which typically involves turning the key to the ‘ON’ position for 10-15 minutes. Start the engine and let it idle to confirm the repair is complete.
Guaranteed Fitment for Your GM Vehicle
This module is a direct replacement for part numbers 16263494, 16265035, 8162634940, 218-11787, and 21811787. Please verify your part number and check the extensive list below to ensure compatibility. This is a reliable solution for a wide range of popular GM models.
Cadillac:
ESCALADE 99-00
Chevrolet / GMC Trucks & SUVs:
ASTRO/SAFARI 99-01
BLAZER/JIMMY S10/S15 98-00 (w/ specific build dates/engines)
BRAVADA / ENVOY 98-00
CHEVROLET/GMC 1500/2500/3500 PICKUPS 99-00 (Gasoline)
SIERRA/SILVERADO 1500 99-00 (6-Cylinder)
S10/S15/SONOMA 98-00 (4.3L)
SUBURBAN 1500/2500 99 (Gasoline)
TAHOE/YUKON 99-00
Chevrolet / GMC Vans:
EXPRESS/SAVANA 1500/2500/3500 99-02 (Gasoline)
Isuzu:
HOMBRE 98-00 (4.3L)
Note: Please match your original part number or consult the detailed fitment list in the product images to confirm an exact match for your vehicle’s options.
Frequently Asked Questions about this 1999-2000 Escalade PCM
Frequently Asked Questions
What does ‘VIN Programmed’ mean?
It means we load the module with your vehicle’s specific Vehicle Identification Number (VIN) and the latest official software from GM. This ensures it communicates perfectly with your truck’s engine, transmission, and security systems right out of the box, just like a new part from the dealer.
Will I need to do anything else after installing it?
In most cases, no. The module is ready to go. Occasionally, certain GM vehicles may require a simple ‘Security Relearn Procedure’ which can be done without any special tools. It typically involves cycling the ignition key and waiting for a few minutes. Instructions are readily available online for your specific model.
How do I provide my VIN?
After you complete your purchase, you will need to send us your 17-digit VIN. We cannot ship your order until we receive this information, as the programming is essential for the part to function correctly.
Is this compatible with other part numbers?
Yes, this PCM is a direct replacement for several part numbers, including 16263494, 8162634940, and 218-11787. If your original module has one of these numbers, this part will work for you.
Can a bad PCM cause my truck to not start?
Absolutely. The PCM controls fuel delivery and ignition spark. If it fails completely, it can prevent the engine from starting, even if the battery and starter are good. This is one of the most common symptoms of a total PCM failure.