2016 Express 2500 Engine Control Module ECM ECU 12643636 | Programmed to VIN

Restore Your Van’s Performance Instantly

Get your 2016 Express 2500 back on the road with this VIN-programmed Engine Control Module (ECM). It’s a direct-fit replacement that solves common issues like stalling, no-starts, and check engine lights. Shipped ready for installation. Order today!

$225.95

+11.99 USPS Priority Shipping

Availability: In stock



SKU: 590-02768-6 Categories: ,
Guaranteed Safe Checkout

Is Your 2016 Express Van Experiencing Unexplained Problems?

The Engine Control Module (ECM), often called the engine computer or ECU, is the electronic brain of your 2016 Chevrolet Express 2500. It’s responsible for managing everything from fuel injection and ignition timing to emissions controls and transmission shifting. When this critical component begins to fail, it can cause a wide range of confusing and frustrating symptoms that can be difficult to diagnose. You might be dealing with a persistent Check Engine Light, poor fuel economy, or even a van that refuses to start. These aren’t just annoyances; they’re signs that your workhorse vehicle’s central nervous system is compromised.

Common Symptoms of a Failing ECM

If your Express 2500 is your livelihood, you can’t afford downtime. Recognizing the signs of a faulty ECM is the first step toward a reliable fix. Look out for these common indicators:

  • ✔ Persistent Check Engine Light (CEL) that won’t clear or returns immediately after reset.
  • ✔ Unexplained drop in fuel efficiency.
  • ✔ Engine stalling, stumbling, or hesitating during acceleration.
  • ✔ Rough or erratic idling.
  • ✔ Difficulty starting the engine, or a complete no-start condition.
  • ✔ Noticeable loss of power and performance.
  • ✔ Harsh or incorrect automatic transmission shifting.
  • ✔ Communication errors with diagnostic scan tools.

From the Diagnostic Bay

We once had a 2016 Express 2500 with the 6.0L engine towed in. The owner, a local contractor, had already replaced the fuel pump, spark plugs, and ignition coils trying to chase down an intermittent stalling issue. The van would run fine for a while, then suddenly die at a stoplight. No specific codes were being stored consistently. After hours of diagnostics, we hooked up a scope to the ECM’s main power and ground circuits. We found that the ECM’s internal voltage regulator was failing intermittently, causing it to shut down randomly. A replacement, VIN-programmed ECM solved the problem instantly. The owner was back on the road the same day, wishing he had started with the vehicle’s brain first.

The Direct-Fit Solution: A VIN-Programmed 2016 Express 2500 Engine Control Module

Don’t let a faulty computer keep your van off the road. This is a direct replacement Engine Control Module for your 2016 Express 2500, identified by part number 12643636 and compatible with a range of other service numbers. The most significant benefit we offer is our complimentary VIN programming service. When you provide us with your vehicle’s Vehicle Identification Number (VIN), we flash the module with the latest, most stable software updates directly from GM. This ensures that the computer is perfectly matched to your van’s specific configuration, including engine size (4.8L or 6.0L), transmission, and factory options. This process eliminates the need for an expensive trip to the dealership for programming.

Plug-and-Play Installation

Because this module arrives pre-programmed for your specific VIN, installation is straightforward. Simply disconnect the battery, locate and swap the old module with the new one, and reconnect the battery. In most cases, you will need to perform a security relearn procedure (often called a Passlock or anti-theft relearn), which is a simple process that can be done in your driveway without any special tools. This procedure syncs the new ECM with your vehicle’s existing anti-theft system. Once completed, your van will be ready to start and run with its performance and reliability restored.

Guaranteed Compatibility

This ECM is a direct replacement for part number 12643636 and also supersedes other common part numbers like 12668866, 12668994, 12663405, 12670335, 22819494, and 12692200. It fits a wide variety of GM vehicles beyond just the Express van, including the Silverado, Sierra, Cruze, and Sonic. By providing your VIN, you guarantee that the unit you receive is 100% correct for your application, taking all the guesswork out of the repair.

Frequently Asked Questions

Do I need to do anything after I install this ECM?

Yes. While we program the module to your VIN, you will still need to perform a security relearn procedure. This is a simple process that pairs the new ECM to your vehicle’s anti-theft system and typically takes 10-30 minutes to complete using only your ignition key. Instructions are readily available online or can be provided upon request.

How do I provide my VIN number?

After you complete your purchase, you can send us a message with your 17-digit VIN. We cannot ship your part until we receive this information, as the programming is essential for the part to function in your vehicle.

Is this a new or used part?

This is a high-quality, genuine OEM part that has been thoroughly inspected, tested, and prepared for your vehicle. It is programmed with the latest GM software for optimal performance and reliability.

Will this fix my specific problem?

This ECM will correct issues directly caused by a failing engine computer. While the symptoms listed are common indicators of ECM failure, we always recommend a proper diagnosis by a qualified mechanic to confirm the ECM is the root cause of your vehicle’s problems before purchasing.

What if I have a different engine in my Express van?

This module is compatible with both the 4.8L and 6.0L engines offered in the 2016 Express 2500 and 3500 vans. The VIN programming process ensures the correct software is loaded for your specific engine and powertrain combination.

Condition

Refurbished

Year

Genuine OEM

Yes

MPN

12643636

Interchange part number

PartNumber

590

Model

express 2500

Year

2012

Brand

GM

Manufacturer Part Number

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