2007 Sierra 3500 Engine Control Module 12597121 Programmed to Your VIN

Restore Your Truck’s Powertrain Health

Get your 2007 Sierra 3500 running right again with this fully programmed Engine Control Module. It arrives flashed to your truck’s specific VIN with the latest GM software, providing a direct-fit solution for stalling, no-start conditions, and persistent check engine lights. Skip the dealership and get a reliable, plug-and-play fix. Order today to restore your truck’s performance and reliability!

$134.99

+11.99 USPS Priority Shipping

Availability: In stock



SKU: 590-00399-43 Categories: ,
Guaranteed Safe Checkout

Is your 2007 Sierra 3500 HD giving you headaches? If you’re dealing with a persistent Check Engine Light, rough idling, stalling, or a frustrating no-start condition, the problem often points directly to a failing Engine Control Module (ECM). As the brain of your truck’s powertrain, a faulty ECM can wreak havoc on performance, fuel economy, and reliability. This isn’t just an inconvenience; it’s a critical component failure that needs a dependable solution.

Forget the expensive and time-consuming trip to the dealership. We offer a direct, reliable replacement: a high-quality 2007 Sierra 3500 Engine Control Module that arrives at your door fully programmed and ready for installation. Simply provide us with your vehicle’s VIN during checkout, and our technicians will flash the module with the latest, most stable GM factory software specific to your truck. This ensures seamless communication between all vehicle systems and restores the performance you depend on.

From the Diagnostic Bay

I remember a 2007 Sierra 3500 with the 6.0L that came into my shop with a bizarre set of symptoms. The owner had already replaced spark plugs and two ignition coils chasing a random misfire, but the truck still ran rough and would occasionally lose all power. The scanner was throwing a P0601 (Internal Control Module Memory Check Sum Error) and a U0100 (Lost Communication With ECM/PCM). These codes are dead giveaways. While other parts can cause misfires, the combination of a memory error and a communication loss pointed straight to the ECM. We installed one of our pre-programmed modules, performed a quick security relearn, and the truck ran like it just rolled off the factory floor. The customer saved hundreds compared to the dealership quote and was back on the road the same day.

Is Your Truck Showing These Symptoms?

A failing ECM can manifest in many ways. If you’re experiencing any of the following, it’s highly likely your module is the culprit:

  • ✔ Check Engine Light is on with codes like P0601, P0602, P0606, or U-series communication codes.
  • ✔ Engine cranks but refuses to start.
  • ✔ Unexplained drops in fuel economy.
  • ✔ Rough or unstable idle.
  • ✔ Engine stalling or hesitating during acceleration.
  • ✔ Harsh or erratic automatic transmission shifting.
  • ✔ Apparent loss of power and poor overall performance.

A Straightforward Guide to Installation

Installing your new 2007 Sierra 3500 Engine Control Module is a job most DIYers can handle with basic tools. For the Sierra/Silverado, the ECM is typically located in the engine bay on the driver’s side, under the battery tray.

  1. Safety First: Always disconnect the negative terminal from your truck’s battery.
  2. Access the Module: You will likely need to remove the battery and the battery tray to gain clear access to the ECM.
  3. Disconnect Connectors: Carefully unlatch and remove the wiring harness connectors from the old ECM. Inspect them for any corrosion or damage.
  4. Swap the Modules: Unbolt and remove the old module. Mount the new, pre-programmed ECM in its place.
  5. Reconnect Everything: Securely plug the wiring harnesses into the new module until they click. Reinstall the battery tray and the battery, then reconnect the negative terminal.
  6. Perform Security Relearn: In many cases, you may need to perform a simple security relearn procedure (often called a Passlock or anti-theft relearn) which can be done without special tools. This typically involves turning the key to the ‘ON’ position for 10-15 minutes. Instructions are widely available online for your specific model.

Will This Module Fit Your Vehicle?

This ECM is a direct replacement for part number 12597121 and is also compatible with part numbers 12589297, 12603892, and 19210738. It fits a wide range of GM vehicles. Please verify your model and options below:

ESCALADE 07 (LH front under battery)
ESCALADE ESV 07 (LH front under battery)
ESCALADE EXT 07 (LH front under battery)
AVALANCHE 1500 07 (LH front under battery)
CORVETTE 06-07 (RH engine compartment)
HUMMER H2 07 (LH front under battery)
SIERRA 1500 PICKUP 07 new style (smooth door skin), (LH front under battery), w/o 4.3L
SIERRA 2500 PICKUP 07 new style (smooth door skin), (LH front under battery), 6.0L
SIERRA 3500 PICKUP 07 new style (smooth door skin), (LH front under battery), 6.0L
SIERRA DENALI 07 new style (smooth door skin), (LH front engine compartment)
SILVERADO 1500 PICKUP 07 new style (smooth door skin), (LH front under battery), w/o 4.3L
SILVERADO 2500 PICKUP 07 new style (smooth door skin), (LH front under battery), 6.0L
SILVERADO 3500 PICKUP 07 new style (smooth door skin), (LH front under battery), 6.0L
SUBURBAN 1500 07 (LH front under battery)
SUBURBAN 2500 07 (LH front under battery)
TAHOE 07 (LH front under battery)
YUKON 07 (LH front under battery)
YUKON XL 1500 07 (LH front under battery)
YUKON XL 2500 07 (LH front under battery)
AURA 07 (RH firewall), 3.5L
EQUINOX 07 (LH engine compartment)
G6 07 (LH front engine compartment), 3.5L or 3.9L
G8 08 6.0L
IMPALA 07 (lower part of air cleaner box), 3.5L or 3.9L
MALIBU 07 3.5L or 3.9L
MONTE CARLO 07 (lower part of air cleaner box), 3.5L or 3.9L
TORRENT 07 (LH engine compartment)
How do I provide my VIN?
After you complete your purchase, you will receive an email with instructions, or you can simply add your 17-digit VIN in the notes section during checkout. We cannot program and ship the module without it.
Is this part difficult to install?
No, this is a plug-and-play part. The physical replacement is straightforward for anyone with basic mechanical skills. The only additional step may be a simple key-cycle security relearn procedure that requires no special tools.
What if my original part number is different?
This module is a direct replacement for several part numbers, including 12589297, 12597121, 12603892, and 19210738. As long as your vehicle is on the compatibility list, this module will function correctly once programmed to your VIN.
Is any additional programming required after I install it?
No. We handle all the programming before shipment using the latest GM software and your VIN. This ensures it’s ready to install right out of the box, saving you a trip to the dealer.
Will this fix my Check Engine Light?
If the Check Engine Light is caused by an internal failure of the ECM (common codes P0601-P0606), then yes, this will resolve the issue. It’s always best to have the codes scanned to confirm the diagnosis before ordering.

Genuine OEM

Yes

Condition

Refurbished

MPN

12597121

Interchange part number

PartNumber

590

Model

Sierra 3500 Pickup

Year

2007

Brand

GM

Manufacturer Part Number

, , ,

Scroll to Top