2006 Isuzu I-350 Powertrain Control Module PCM 12591647

Get Your Truck Back on the Road Fast!

Restore your truck’s performance with this pre-programmed Powertrain Control Module. It’s flashed to your specific VIN with the latest GM software, ensuring a perfect, plug-and-play fit. Skip the expensive dealership programming and fix stalling, misfires, and check engine lights yourself. Provide your VIN at checkout and get back to driving with confidence!

$184.95

+11.99 USPS Priority Shipping

Availability: In stock



Guaranteed Safe Checkout

Is Your Isuzu I-350 Running Rough? The PCM Might Be the Culprit.

If you’re experiencing baffling engine problems like stalling, erratic shifting, a persistent check engine light, or even a no-start condition, the issue may lie with the heart of your vehicle’s electronics: the Powertrain Control Module (PCM). As the central computer for your engine and transmission, a failing PCM can cause a wide range of frustrating and difficult-to-diagnose symptoms. This replacement module is the definitive solution to restore your truck’s performance, reliability, and drivability.

What is a Powertrain Control Module?

Think of the PCM as the brain of your 2006 Isuzu I-350. It constantly receives data from sensors all over your vehicle—from the oxygen sensors in your exhaust to the speed sensors in your transmission. It then uses this information to make millions of calculations per second, precisely controlling critical functions like fuel injection, ignition timing, variable valve timing, and automatic transmission shift points. When it functions correctly, your truck runs smoothly and efficiently. When it fails, the entire powertrain system can be thrown into disarray.

Expert Pro Tip

Before condemning your PCM, always perform a thorough check of the vehicle’s battery, alternator, and all primary ground connections. A weak power supply or a corroded ground strap (especially the one from the engine block to the chassis) can mimic PCM failure and cause a host of electrical gremlins. A simple voltage drop test on the main grounds can save you hundreds of dollars and hours of frustration.

Symptoms of a Failing 2006 Isuzu I-350 PCM

  • ✔ Check Engine Light: Your check engine light is on, and you may have codes related to PCM internal failure, processor faults, or communication errors (U-codes).
  • ✔ Engine Stalling or Misfiring: The engine may stall intermittently, either while driving or at idle. You may also experience random misfires that don’t seem to be related to spark plugs or coils.
  • ✔ No-Start Condition: The engine cranks but refuses to start. This can be due to the PCM not commanding the fuel pump or injectors to operate.
  • ✔ Poor Performance & Fuel Economy: A noticeable drop in power, acceleration, and a significant increase in fuel consumption are common signs of a struggling module.
  • ✔ Erratic Transmission Shifting: The PCM also controls the transmission. You might experience harsh shifts, delayed engagement, or the transmission getting stuck in one gear (limp mode).
  • ✔ Failed Emissions Test: An improperly functioning PCM cannot manage the emissions systems correctly, leading to an automatic failure at the testing station.

The Simple, Reliable Solution: A VIN-Programmed Module

Forget expensive trips to the dealership and the hassle of finding a shop with the right programming tools. We make the process simple. When you order this 2006 Isuzu I-350 PCM, you provide us with your vehicle’s 17-digit Vehicle Identification Number (VIN). Our technicians then flash the unit with the latest, most up-to-date GM factory software specific to your exact truck. This ensures that the module is calibrated for your engine, transmission, and all factory-installed options.

This module arrives at your door ready for a straightforward installation. In most cases, it’s a plug-and-play process. Once installed, you may need to perform a simple security relearn procedure (often called VATS or Passlock relearn), which typically involves turning the key on and off in a specific sequence. This procedure pairs the new module to your vehicle’s anti-theft system and can be done in your own driveway without any special tools.

Guaranteed Fitment for Part Number 12591647

This module is a direct replacement for a wide range of GM trucks and SUVs. It is compatible with the following part numbers:

12569773, 12588650, 12589311, 12589585, 12591647, 12591648, 12593531, 12593532, 12594430, 12594431, 12596783, 12596784, 12597521, 12597776, 12597777, 12600818, 12604438, 12604439, 12606369, 12606373, 12606374, 12606398, 12606399, 19209820, 19209821

It will fit the following vehicles:

  • Chevrolet Colorado (2004-2006)
  • GMC Canyon (2004-2006)
  • Hummer H3 (2006)
  • Isuzu I-280 (2006)
  • Isuzu I-350 (2006)
  • Buick Rainier (2006, 4.2L)
  • Chevrolet Trailblazer & Trailblazer EXT (2006, 4.2L)
  • GMC Envoy & Envoy XL (2006, 4.2L)
  • Isuzu Ascender (2006, 4.2L)
  • Saab 9-7x (2006, 6 cylinder)

Frequently Asked Questions

Why do you need my VIN?

Your Vehicle Identification Number (VIN) allows us to load the exact factory software and calibrations for your truck. This includes specifics for the engine, transmission, tire size, gear ratio, and emissions equipment, ensuring perfect compatibility and performance right out of the box.

Is this module difficult to install?

The physical installation is straightforward for someone with basic mechanical skills. On the 2006 Isuzu I-350, the PCM is typically located on the right-hand (passenger side) firewall in the engine bay. The process involves disconnecting the battery, unplugging the electrical connectors, unbolting the old module, and then reversing the process. No special tools are required for the physical swap.

Will I need to do anything after installation?

After installing the new PCM, you will likely need to perform a security relearn procedure to sync the module with your vehicle’s anti-theft system. This is a simple key-on/key-off sequence that takes about 30 minutes. In some cases, a Crankshaft Position Sensor (CASE) relearn may be needed, which requires a diagnostic scan tool, but the vehicle will typically run and drive without it.

Is this a guaranteed fix for my check engine light?

This module will resolve any issues, symptoms, and check engine light codes that are directly caused by a faulty PCM. However, it will not fix problems related to other bad sensors, wiring issues, or mechanical failures. Proper diagnosis is key to ensuring you are purchasing the correct part for your vehicle’s problem.

What is the difference between a PCM, ECM, and ECU?

These terms are often used interchangeably. ECU (Electronic Control Unit) is a generic term. ECM (Engine Control Module) typically controls only engine functions. A PCM (Powertrain Control Module), like the one in your vehicle, is more integrated and controls both the engine and the transmission functions.

Condition

Refurbished

Year

Genuine OEM

Yes

MPN

12591647

Brand

GM

Year

2006

Model

isuzu-i-350

Hardware Type

Interchange part number

Manufacturer Part Number

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