Is Your Isuzu I-350 Running Rough?
A failing Powertrain Control Module (PCM), also known as an Electronic Control Module (ECM), can be the source of countless frustrating and difficult-to-diagnose issues. As the central computer of your truck, the PCM governs everything from fuel injection and spark timing to transmission shift points and emissions controls. When it starts to fail, you might experience a sudden drop in performance, poor fuel economy, or even a no-start condition that leaves you stranded. This isn’t just an inconvenience; it’s a critical failure that compromises your vehicle’s reliability and drivability.
The Plug-and-Play Solution for Your Truck
This replacement Powertrain Control Module is the definitive solution to restore your vehicle’s factory performance. We take the guesswork and hassle out of the repair process. Unlike a generic module from a parts store or a salvage yard, this unit comes professionally programmed to your vehicle’s specific Vehicle Identification Number (VIN). This crucial step ensures that the module communicates flawlessly with all other systems in your truck, from the anti-lock brakes to the instrument cluster. By providing us with your VIN during checkout, you receive a module that is ready for installation right out of the box, saving you a costly trip to the dealership for programming.
From the Diagnostic Bay
We had a 2006 Chevy Colorado (which shares the same platform and PCM as the Isuzu I-350) come into the shop on a tow truck. The customer had spent weeks chasing a ghost—an intermittent no-start condition with no check engine light. He had replaced the battery, starter, and fuel pump to no avail. After hooking up our professional scan tool, we noticed erratic data from the PCM; it would occasionally lose communication with the rest of the vehicle. We suspected an internal PCM failure. Instead of a costly new unit from the dealer, we sourced a pre-programmed module like this one. After a simple 15-minute swap and a quick security relearn, the truck fired up instantly and ran perfectly. The customer was thrilled to have a reliable truck again without the massive dealership bill.
Common Symptoms of a Failing 2006 Isuzu I-350 PCM
If you’re experiencing any of the following issues, a faulty PCM could be the culprit. A failing module can often mimic other problems, making diagnosis tricky. Look out for these common warning signs:
- ✔ Check Engine Light is illuminated, often with communication-related error codes (U-codes).
- ✔ Engine stalling, stumbling, or misfiring for no apparent reason.
- ✔ Harsh or erratic automatic transmission shifting.
- ✔ A sudden, unexplained decrease in fuel mileage.
- ✔ The engine cranks but refuses to start.
- ✔ Intermittent electrical issues or warning lights on the dashboard.
- ✔ Failure to pass an emissions test.
Guaranteed Compatibility and Reliability
This module is a direct replacement for a wide range of GM and Isuzu trucks and SUVs, ensuring a perfect fit and function. It is compatible with multiple original equipment part numbers, including 19209821 and many others listed below. Each unit is meticulously inspected and tested to ensure it meets or exceeds original performance standards. We load it with the latest GM-certified software updates, which can often resolve factory bugs and improve overall vehicle operation.
This module fits the following vehicles:
- 2004-2006 Chevrolet Colorado
- 2004-2006 GMC Canyon
- 2006 Hummer H3
- 2006 Isuzu I-280
- 2006 Isuzu I-350
- 2006 Buick Rainier (4.2L)
- 2006 GMC Envoy / Envoy XL (4.2L)
- 2006 Chevrolet Trailblazer / Trailblazer EXT (4.2L)
- 2006 Isuzu Ascender (4.2L)
- 2006 Saab 9-7x (6 cylinder)
This unit replaces part numbers: 12569773, 12588650, 12589311, 12589585, 12591647, 12591648, 12593531, 12593532, 12594430, 12594431, 12596783, 12596784, 12597521, 12597776, 12597777, 12600818, 12604438, 12604439, 12606369, 12606373, 12606374, 12606398, 12606399, and 19209820.
Frequently Asked Questions
Do I need to do any programming myself?
No. This module comes pre-programmed to your vehicle’s VIN. You just need to provide us with your VIN when you place your order. In some cases, a simple security relearn procedure (often called a key relearn) may be required after installation, which can be done without any special tools.
Where is the PCM located on my 2006 Isuzu I-350?
On the 2006 Isuzu I-350, as well as the Chevy Colorado, GMC Canyon, and Hummer H3, the PCM is typically located on the right-hand (passenger) side of the firewall in the engine bay.
Is this a simple DIY installation?
For someone with basic mechanical skills, this is a straightforward job. It involves disconnecting the vehicle’s battery, unplugging the electrical connectors from the old PCM, unbolting it, and then installing the new one in the reverse order. It typically takes less than 30 minutes.
What if my original part number is not on your list?
The part numbers listed are the most common, but there may be others. If your vehicle model and year match our fitment list, this module will work. The VIN programming ensures it is correctly configured for your specific vehicle options.
Will this fix my check engine light?
If the check engine light is caused by a faulty PCM, then yes, this part will resolve the issue. It’s important to have your vehicle properly diagnosed to confirm the PCM is the root cause of the problem before ordering.