Restore Peak Performance to Your 2006 Isuzu I-350
Is your truck suffering from erratic behavior, a persistent check engine light, or poor fuel economy? These are classic signs of a failing Powertrain Control Module (PCM), the electronic brain of your vehicle’s engine and transmission. This replacement PCM, part number 12606374, is the definitive solution to restore your truck’s original performance, drivability, and reliability. We take the guesswork and hassle out of the repair by programming the module specifically to your vehicle’s Vehicle Identification Number (VIN) before it ships. This ensures a seamless, plug-and-play installation without requiring an expensive trip to the dealership for programming.
We had a 2006 Chevy Colorado come in with what the owner was sure was a bad transmission. It was shifting hard, sometimes getting stuck in gear, and the check engine light was on. He had already replaced a couple of solenoids with no luck. After hooking up our scanner, we noticed erratic data coming from the PCM and communication dropouts. Instead of a costly transmission rebuild, the root cause was a failing PCM corrupting the signals to the transmission. We installed a VIN-programmed module just like this one, and the truck drove like new. It’s a powerful reminder that the PCM controls everything, and what seems like a major mechanical failure can often be an electronic one.
Is Your PCM Failing? Common Symptoms
A faulty PCM can manifest in numerous ways, often mimicking other component failures. If you’re experiencing any of the following issues, your engine computer may be the culprit:
- ✔ Persistent Check Engine Light (CEL) with various trouble codes.
- ✔ Poor engine performance, including hesitation, stalling, or rough idling.
- ✔ Decreased fuel efficiency for no apparent reason.
- ✔ Harsh or erratic automatic transmission shifting.
- ✔ The engine cranks but refuses to start.
- ✔ Failure to pass state emissions tests.
- ✔ Communication errors with diagnostic scan tools.
The Critical Role of VIN Programming
Modern vehicles like your Isuzu I-350 have complex systems that are tied directly to the VIN. This includes anti-theft systems (Passlock/VATS), specific engine and transmission calibrations, and optional equipment. Simply installing a used, non-programmed module will result in a no-start condition or severe operational problems. Our process eliminates this barrier. By providing your VIN during checkout, you receive a module that is a true plug-and-play replacement. We flash it with the latest GM-certified software updates, which can often resolve underlying drivability issues you may not have even been aware of. This is the most reliable and efficient way to replace your 2006 Isuzu I-350 PCM.
Direct-Fit for Your Vehicle
This Powertrain Control Module is a guaranteed fit for a range of GM trucks and SUVs. It is located on the right-hand (passenger side) firewall on your Isuzu I-350, Isuzu I-280, Chevy Colorado, GMC Canyon, and Hummer H3. On other compatible models like the Trailblazer, Envoy, and Rainier, it is found on the left-hand (driver side) of the engine. Please verify your original part number against our comprehensive cross-reference list below to ensure compatibility.
Compatible Part Numbers:
This module replaces the following GM and Isuzu part numbers: 12569773, 12588650, 12589311, 12589585, 12591647, 12591648, 12593531, 12593532, 12594430, 12594431, 12596783, 12596784, 12597521, 12597776, 12597777, 12600818, 12604438, 12604439, 12606369, 12606373, 12606374, 12606398, 12606399, 19209820, 19209821.
Vehicle Fitment List:
- ✔ Chevrolet Colorado: 2004-2006 (RH firewall)
- ✔ GMC Canyon: 2004-2006 (RH firewall)
- ✔ Buick Rainier: 2006 (4.2L, LH engine)
- ✔ Hummer H3: 2006 (RH firewall)
- ✔ Isuzu Ascender: 2006 (4.2L, LH engine)
- ✔ Isuzu I-280: 2006 (RH firewall)
- ✔ Isuzu I-350: 2006 (RH firewall)
- ✔ Saab 9-7X: 2006 (6 cylinder, LH engine)
Don’t let a faulty computer keep your truck off the road. Order this professionally programmed 2006 Isuzu I-350 PCM today and restore the smooth, reliable operation you depend on.
Frequently Asked Questions
What is a PCM and what does it do?
The Powertrain Control Module (PCM) is the main computer that controls your vehicle’s engine and transmission. It manages critical functions like fuel injection, ignition timing, emissions systems, and automatic transmission shift points to ensure optimal performance and efficiency.
Is any additional programming required after installation?
No. We program the module to your specific VIN before shipping. This means it arrives ready for a plug-and-play installation. In most cases, you will not need to perform any additional procedures, though some vehicles may require a simple security relearn procedure which can be done without any special tools.
How do I provide my VIN?
After you complete your purchase, you will need to send us your 17-digit Vehicle Identification Number (VIN). You can typically find your VIN on your vehicle’s registration, insurance card, or on a plate on the driver’s side dashboard visible through the windshield.
Will this fix my check engine light?
If the check engine light is caused by a faulty PCM, then this replacement part will solve the issue. However, the check engine light can be triggered by many other failing components. It is always best to have the vehicle properly diagnosed to confirm the PCM is the root cause of the problem.
What happens if I don’t provide my VIN?
We cannot ship the module without your VIN. The programming is essential for the part to function in your vehicle. We will hold your order and contact you to obtain the VIN to ensure you receive a correctly configured part.