Restore Peak Performance to Your 2006 Isuzu I-350
Is your Isuzu I-350 suffering from frustrating issues like a persistent check engine light, rough idling, poor fuel economy, or even a no-start condition? The Powertrain Control Module (PCM), the central computer of your vehicle, is often the root cause. This vital component manages everything from fuel injection and ignition timing to transmission shifting. When it fails, the symptoms can be widespread and difficult to diagnose. This listing offers a direct, reliable solution: a replacement PCM, part number 12606373, professionally programmed to your truck’s specific Vehicle Identification Number (VIN).
We take the guesswork and high dealership costs out of the equation. By providing us with your VIN during checkout, you receive a module loaded with the latest GM-authorized software calibrations for your exact vehicle configuration. This ensures seamless integration and restores the precise operational parameters your truck was designed with from the factory, getting you back on the road with confidence.
Diagnosing a Faulty 2006 Isuzu I-350 PCM
A failing powertrain control module can manifest in numerous ways, often mimicking other sensor or component failures. If you’ve checked sensors and wiring but the problems persist, it’s time to consider the PCM. This module is the definitive solution for restoring your vehicle’s engine management system to its original, optimal state.
Expert Pro Tip
Expert Pro Tip
Before condemning your PCM, always perform a thorough check of the vehicle’s main power and ground connections. A corroded ground strap or a loose battery terminal can cause low voltage issues that mimic PCM failure. Use a multimeter to perform a voltage drop test on the main power and ground circuits to the module. A reading of more than 0.2 volts indicates excessive resistance that must be corrected first. This simple diagnostic step can save you from replacing a perfectly functional computer.
Common Symptoms of a Failing PCM
- ✔ Persistent Check Engine Light (CEL) that won’t clear, or returns immediately.
- ✔ No-start or hard-start conditions where the engine cranks but fails to fire up.
- ✔ Unexplained engine stalling, rough idling, or hesitation during acceleration.
- ✔ A noticeable decrease in fuel efficiency.
- ✔ Erratic or harsh automatic transmission shifting.
- ✔ Communication errors when trying to connect a diagnostic scan tool.
- ✔ Multiple unrelated trouble codes being stored simultaneously.
A Simple, Programmed Solution
Forget about costly towing fees and long waits at the dealership. Our service is designed for convenience and reliability. Once you place your order, simply provide us with your vehicle’s VIN. Our technicians will then flash the module with the correct, updated software from GM. The module you receive will be ready for installation, tailored specifically for your 2006 Isuzu I-350. While the physical installation is straightforward, please note that a security relearn procedure may be necessary for your vehicle to start. This is a standard industry procedure that can often be performed without special tools.
Wide Compatibility
This PCM is a direct replacement for a range of part numbers and fits several GM vehicles from this era. Please verify your part number against the list below to ensure compatibility.
Replaces Part Numbers: 12569773, 12588650, 12589311, 12589585, 12591647, 12591648, 12593531, 12593532, 12594430, 12594431, 12596783, 12596784, 12597521, 12597776, 12597777, 12600818, 12604438, 12604439, 12606369, 12606373, 12606374, 12606398, 12606399, 19209820, 19209821
Fits The Following Vehicles:
- 2004-2006 Chevrolet Colorado
- 2004-2006 GMC Canyon
- 2006 Buick Rainier (4.2L)
- 2006 Hummer H3
- 2006 Isuzu Ascender (4.2L)
- 2006 Isuzu I-280
- 2006 Isuzu I-350
- 2006 Chevrolet Trailblazer & Trailblazer EXT (4.2L)
- 2006 GMC Envoy & Envoy XL (4.2L)
- 2006 Saab 9-7x (6 cylinder)
Frequently Asked Questions
Expert Pro Tip
Before condemning your PCM, always perform a thorough check of the vehicle’s main power and ground connections. A corroded ground strap or a loose battery terminal can cause low voltage issues that mimic PCM failure. Use a multimeter to perform a voltage drop test on the main power and ground circuits to the module. A reading of more than 0.2 volts indicates excessive resistance that must be corrected first. This simple diagnostic step can save you from replacing a perfectly functional computer.