Is your 2006 Isuzu I-350 running rough, shifting erratically, or showing a persistent check engine light? These are classic signs of a failing Powertrain Control Module (PCM), the central computer that manages your truck’s engine and transmission. A faulty PCM can lead to a cascade of frustrating issues, from poor fuel economy to a complete no-start condition. Don’t let a failing computer keep your reliable Isuzu off the road. This is your direct-fit, plug-and-play solution to restore your vehicle’s performance and dependability.
This module is a genuine replacement, meticulously programmed to your vehicle’s specific Vehicle Identification Number (VIN). This critical step ensures that the computer has the correct software and calibrations for your truck’s exact configuration, including engine size, transmission type, and emissions equipment. By providing us with your VIN upon purchase, you receive a unit that is ready for installation right out of the box, eliminating the need for expensive trips to the dealership for programming.
Expert Pro Tip
Expert Pro Tip
After installing the new PCM, it’s crucial to perform a full system reset. Disconnect the negative battery terminal for at least 30 minutes before starting the installation. Once the new module is connected, reconnect the battery. This process clears any stored fault codes in other modules and allows the vehicle’s entire electronic system to recognize and communicate properly with the new PCM from a clean slate. This can prevent communication errors and ensure a smooth first start.
Diagnosing a Faulty 2006 Isuzu I-350 PCM
The PCM is the brain of your vehicle’s operation. When it begins to fail, the symptoms can be varied and sometimes misleading. If you’re experiencing any of the issues below, your PCM is a likely culprit. This module is the definitive solution for restoring communication and control over your powertrain.
Common Symptoms of PCM Failure
- ✔ Check Engine Light: The most common indicator, often with codes related to sensors, emissions, or internal processor errors.
- ✔ Poor Engine Performance: You may notice a significant loss of power, hesitation during acceleration, or rough idling.
- ✔ Reduced Fuel Economy: A failing PCM can’t properly manage the air-fuel mixture, leading to your truck consuming more gasoline than usual.
- ✔ Erratic Shifting or Transmission Issues: The PCM also controls the transmission. Hard shifts, getting stuck in gear, or failure to shift are common symptoms.
- ✔ Engine Stalling: The engine may stall intermittently, especially when coming to a stop or at idle.
- ✔ No-Start Condition: In severe cases, the PCM can fail completely, preventing the engine from starting at all by failing to control fuel or spark.
- ✔ Communication Errors: Your mechanic’s scan tool may be unable to communicate with the PCM, a clear sign of an internal failure.
Broad Compatibility and Guaranteed Fitment
This Powertrain Control Module isn’t just for the Isuzu I-350. It is a direct replacement for a wide range of GM trucks and SUVs from the same era that share the GMT355 and GMT360 platforms. This unit is compatible with numerous part numbers, ensuring a perfect match for your vehicle. Please verify your part number against the list below or confirm your vehicle is listed in our fitment guide.
Compatible Part Numbers: 12569773, 12588650, 12589311, 12589585, 12591647, 12591648, 12593531, 12593532, 12594430, 12594431, 12596783, 12596784, 12597521, 12597776, 12597777, 12600818, 12604438, 12604439, 12606369, 12606373, 12606374, 12606398, 12606399, 19209820, 19209821.
Fits Models Including:
- 2004-2006 Chevrolet Colorado
- 2004-2006 GMC Canyon
- 2006 Buick Rainier (4.2L)
- 2006 Hummer H3
- 2006 Isuzu Ascender (4.2L)
- 2006 Isuzu I-280 & I-350
- 2006 Chevrolet Trailblazer & Trailblazer EXT (4.2L)
- 2006 GMC Envoy & Envoy XL (4.2L)
- 2006 Saab 9-7x (6 cylinder)
Frequently Asked Questions
Expert Pro Tip
After installing the new PCM, it’s crucial to perform a full system reset. Disconnect the negative battery terminal for at least 30 minutes before starting the installation. Once the new module is connected, reconnect the battery. This process clears any stored fault codes in other modules and allows the vehicle’s entire electronic system to recognize and communicate properly with the new PCM from a clean slate. This can prevent communication errors and ensure a smooth first start.