Is your 2006 Isuzu I-350 running rough, stalling, or displaying a persistent check engine light? These are classic signs of a failing Powertrain Control Module (PCM), the central computer responsible for managing your engine’s performance, fuel efficiency, and emissions. Don’t let a faulty module keep your reliable truck off the road. This replacement PCM, part number 12591648, is the definitive solution to restore your vehicle’s original performance and reliability.
This isn’t just a generic, off-the-shelf part. We program this module specifically for your vehicle using your unique Vehicle Identification Number (VIN). This critical step ensures that the PCM has the correct software and calibrations for your truck’s specific engine, transmission, and options. By flashing it with the latest GM-authorized updates, we ensure optimal performance and address any known issues from the original factory software. The result is a component that integrates seamlessly with your vehicle, just like the original did when it was new.
From the Diagnostic Bay
We had a 2006 Chevy Colorado (which uses the same platform as the I-350) come into the shop with a no-start condition. The owner had already replaced the battery, alternator, and starter to no avail. The diagnostic scanner was unable to communicate with the engine computer. This is a tell-tale sign. Before condemning the module, we always check the basics: power and ground connections to the PCM. We found solid voltage and clean grounds, confirming the internal failure of the original unit. After installing one of our pre-programmed modules and performing the quick security relearn, the truck fired right up and ran perfectly. It saved the owner from more guesswork and unnecessary parts expenses.
Common Symptoms of a Failing PCM
- ✔ Check Engine Light: The most common indicator, often with communication-related error codes (U-codes) or performance codes.
- ✔ Engine Stalling or Misfiring: The engine may stall intermittently, run rough, or misfire as the PCM struggles to control fuel and spark.
- ✔ No-Start Condition: A completely failed PCM can prevent the engine from starting at all.
- ✔ Poor Fuel Economy: Incorrect fuel and air calculations can lead to a noticeable drop in MPG.
- ✔ Transmission Shifting Problems: The PCM also communicates with the transmission controller, and a failure can cause harsh or erratic shifting.
- ✔ Failed Emissions Test: An improperly functioning module will not be able to manage the emissions systems correctly, leading to a failed test.
Why a Programmed 2006 Isuzu I-350 PCM is Essential
The 2006 Isuzu I-350 PCM is more than just a piece of hardware; it’s the brain of your vehicle’s operation. Without correct programming, a replacement module simply will not work. It won’t recognize your keys, your transmission, or other critical vehicle systems. Our professional programming service eliminates the need for an expensive trip to the dealership. We handle the complex software flashing process for you, so when the part arrives, it’s ready for installation. All you need to do is provide us with your VIN during the checkout process, and we’ll take care of the rest.
Simple Installation Process
Once you receive your pre-programmed module, the physical installation is straightforward. It is typically located on the right-hand side of the firewall in the engine bay.
- Disconnect the vehicle’s battery.
- Carefully unplug the wiring harnesses from the old module.
- Unbolt and remove the old module.
- Bolt the new module in its place.
- Securely reconnect the wiring harnesses.
- Reconnect the battery.
After installation, you may need to perform a simple security relearn procedure (often called a key relearn or anti-theft relearn). This process syncs the new PCM with your vehicle’s anti-theft system and can usually be done in your driveway with no special tools. Instructions are readily available online or we can help guide you.
Guaranteed Fitment
This module is a direct replacement for a wide range of vehicles and part numbers. Please verify that your vehicle is on the list below. This part is compatible with the following part numbers: 12569773, 12588650, 12589311, 12589585, 12591647, 12591648, 12593531, 12593532, 12594430, 12594431, 12596783, 12596784, 12597521, 12597776, 12597777, 12600818, 12604438, 12604439, 12606369, 12606373, 12606374, 12606398, 12606399, 19209820, 19209821.
This Electronic Control Module fits:
- 2004-2006 Chevrolet Colorado
- 2004-2006 GMC Canyon
- 2006 Buick Rainier (4.2L)
- 2006 Hummer H3
- 2006 Isuzu Ascender (4.2L)
- 2006 Isuzu I-280
- 2006 Isuzu I-350
- 2006 GMC Envoy & Envoy XL (4.2L)
- 2006 Chevrolet Trailblazer & Trailblazer EXT (4.2L)
- 2006 Saab 9-7x (6-cylinder)
By choosing this pre-programmed 2006 Isuzu I-350 PCM, you are getting a reliable, cost-effective solution to get your truck back in top condition. Eliminate the guesswork and order with confidence today.
Frequently Asked Questions
Do I need to have this module programmed?
No, we handle all the programming for you before shipment. Simply provide your vehicle’s VIN when you place your order, and it will arrive ready to be installed.
What is a VIN and why do you need it?
The VIN (Vehicle Identification Number) is a unique 17-digit code for your specific truck. It tells us everything we need to know about its engine, transmission, and factory options, allowing us to load the exact correct software onto your new PCM.
Will this fix my check engine light?
If the check engine light is on due to a faulty PCM, this part will resolve the issue. However, it’s always best to have the codes read by a scanner to confirm the source of the problem before ordering.
What is the security relearn procedure?
It’s a simple procedure that syncs the new PCM to your vehicle’s anti-theft system so it will recognize your keys. It typically involves turning the key to the ‘ON’ position for 10-15 minutes, then off, and repeating two more times. No special tools are required.
Where is the PCM located on my 2006 Isuzu I-350?
The Powertrain Control Module is typically located in the engine compartment, mounted to the right-hand (passenger side) of the firewall.