2006 Isuzu I-350 PCM Powertrain Control Module 12589585

Restore Your Truck’s Performance

Get your 2006 Isuzu I-350 running like new with this Powertrain Control Module. It comes pre-programmed to your vehicle’s VIN with the latest GM software updates, ensuring a perfect match and reliable performance. Simply provide your VIN at checkout and get back on the road fast!

$184.95

+11.99 USPS Priority Shipping

Availability: In stock



Guaranteed Safe Checkout

The Brain of Your Truck: Restoring Performance to Your 2006 Isuzu I-350

The Powertrain Control Module, or PCM, is the central command center for your 2006 Isuzu I-350. It’s a sophisticated computer that manages everything from fuel injection and ignition timing to transmission shifting and emissions control. When it begins to fail, the symptoms can be widespread and frustrating, often leading to a vehicle that is unreliable or undrivable. This replacement PCM is the definitive solution to get your truck operating at peak efficiency again, just as the manufacturer intended.

This isn’t just a generic, off-the-shelf part. We take the guesswork out of the repair by pre-programming this module specifically for your vehicle using the VIN you provide. This critical step ensures that all factory settings, security information (anti-theft), and operational parameters are perfectly matched to your truck’s unique configuration. Furthermore, we flash it with the latest GM-released software updates, which can resolve underlying drivability issues and improve overall performance and fuel economy. You receive a component that is ready for installation, saving you a costly trip to the dealership for programming.

Expert Pro Tip

Expert Pro Tip

Before condemning your PCM, perform a thorough check of all power and ground connections at the battery, engine block, and chassis. A loose or corroded ground wire is a common issue on these trucks and can create erratic electrical problems that mimic a failing computer. A few minutes with a wire brush and a wrench can sometimes save you hundreds of dollars.

Is Your Isuzu I-350 Showing Signs of PCM Failure?

A failing PCM can manifest in numerous ways, often starting as intermittent issues that become progressively worse. If you’re experiencing any of the following problems, a faulty engine computer could be the culprit:

  • ✔ Persistent Check Engine Light (CEL) with various trouble codes, especially those related to internal module failure, communication errors (U-codes), or sensor reference voltage.
  • ✔ Rough or erratic engine idling and stalling.
  • ✔ Noticeable decrease in fuel economy.
  • ✔ Harsh or incorrect automatic transmission shifting.
  • ✔ Engine misfires or a feeling of hesitation during acceleration.
  • ✔ Complete no-start or crank-no-start condition where the engine turns over but won’t fire up.
  • ✔ Communication issues with diagnostic scan tools.

The Direct-Fit Solution: A Programmed 2006 Isuzu I-350 PCM

Choosing the right replacement is crucial for a lasting repair. This module is a direct-fit replacement for a wide range of original equipment part numbers, ensuring seamless integration with your vehicle’s existing systems. By providing us with your VIN, you guarantee that the 2006 Isuzu I-350 PCM you receive is calibrated for your specific engine, transmission, and emissions equipment. This attention to detail eliminates compatibility problems and ensures your truck runs smoothly from the moment of installation.

Simple Installation Process

Once you receive your programmed module, the physical installation is straightforward. It is typically located on the right-hand (passenger side) firewall. After disconnecting the battery, you simply unplug the electrical connectors from the old unit, unbolt it, and install the new one in its place. After installation, a ‘CASE Relearn’ (Crankshaft Position System Variation Learning) procedure is often required. This can be performed by most professional scan tools and syncs the new PCM with the crankshaft position sensor, ensuring accurate misfire detection and engine timing. Some vehicles may also require a security relearn, which can often be done without a scan tool by cycling the ignition key.

Guaranteed Compatibility

This module is a direct replacement for an extensive list of part numbers, making it a versatile solution for many GM trucks and SUVs from this era. It is guaranteed to fit and function correctly in the following vehicles:

  • Chevrolet Colorado: 2004-2006
  • GMC Canyon: 2004-2006
  • Hummer H3: 2006
  • Isuzu I-280: 2006
  • Isuzu I-350: 2006
  • Buick Rainier: 2006 (4.2L)
  • Chevrolet Trailblazer & Trailblazer EXT: 2006 (4.2L)
  • GMC Envoy & Envoy XL: 2006 (4.2L)
  • Isuzu Ascender: 2006 (4.2L)
  • Saab 9-7x: 2006 (6 cylinder)

It replaces the following part numbers: 12569773, 12588650, 12589311, 12589585, 12591647, 12591648, 12593531, 12593532, 12594430, 12594431, 12596783, 12596784, 12597521, 12597776, 12597777, 12600818, 12604438, 12604439, 12606369, 12606373, 12606374, 12606398, 12606399, 19209820, 19209821.

Frequently Asked Questions

Expert Pro Tip

Before condemning your PCM, perform a thorough check of all power and ground connections at the battery, engine block, and chassis. A loose or corroded ground wire is a common issue on these trucks and can create erratic electrical problems that mimic a failing computer. A few minutes with a wire brush and a wrench can sometimes save you hundreds of dollars.

Condition

Refurbished

Year
Genuine OEM

Yes

MPN

12569773

Brand

GM

Year

2006

Model

isuzu-i-350

Hardware Type

Interchange part number

Manufacturer Part Number

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