Is Your 2006 Isuzu I-350 Giving You Headaches?
If you’re dealing with a frustrating no-start condition, erratic engine behavior, or a persistent Check Engine Light on your 2006 Isuzu I-350, the root cause is often the Powertrain Control Module (PCM). As the central computer for your truck’s engine and transmission, when it starts to fail, it can create a cascade of baffling problems. In my 20+ years as a diagnostic technician, I’ve seen these GM-platform trucks come into the bay with symptoms that leave owners scratching their heads: harsh shifting, abysmal fuel economy, and stalling for no apparent reason.
The PCM is responsible for managing everything from fuel injector pulse width to ignition timing and transmission shift points. Over time, heat cycles, vibrations, and voltage spikes can damage the delicate internal circuits, leading to a complete breakdown in communication and control.
Expert Pro Tip: Check Your Grounds First!
Before you condemn your PCM, do yourself a favor and check the main engine and body ground connections. On these Isuzu I-350 / Colorado / Canyon platforms, a corroded or loose ground strap (especially the one near the RH firewall where the PCM is located) can mimic PCM failure perfectly. I’ve saved customers hundreds of dollars by spending 10 minutes with a wire brush and a wrench. A solid ground is critical for any computer to function correctly.
The Direct-Fit, Programmed Solution
This isn’t just a replacement part; it’s a complete, ready-to-install solution for your truck. We take a genuine OEM module and program it specifically to your vehicle’s Vehicle Identification Number (VIN). This critical step ensures that the computer has the correct software and calibrations for your I-350’s specific engine, transmission, and factory options. We flash it with the latest GM-released software updates, which often correct drivability issues and improve performance beyond the original factory programming.
Why is VIN Programming So Important?
A PCM from a junkyard or a non-programmed unit won’t work correctly. It will contain the wrong VIN and security information, preventing your truck from starting. It may also have incorrect calibrations for your engine size or emissions equipment, leading to poor performance and more warning lights. Our service eliminates the need for an expensive trip to the dealership for programming. You get a module that is truly plug-and-play.
Common Symptoms of a Failing 2006 Isuzu I-350 PCM:
- โ Engine cranks but will not start.
- โ Persistent and multiple, unrelated Diagnostic Trouble Codes (DTCs).
- โ Communication errors with diagnostic scan tools.
- โ Harsh or erratic automatic transmission shifting.
- โ Drastic decrease in fuel mileage.
- โ Stalling, stumbling, or hesitation during acceleration.
- โ Check Engine Light is on with codes like P0601, P0606, or other internal processor faults.
Simple Installation Process:
After you place your order, simply send us your vehicle’s 17-digit VIN. Our technicians will handle the programming, and the module will be shipped directly to you. Installation typically involves disconnecting the battery, unplugging the electrical connectors from the old PCM, unbolting it from its mount on the right-hand firewall, and installing the new one in its place. Once installed, you may need to perform a simple security relearn procedure, which can be done without any special tools and takes about 30 minutes. We provide instructions for this process.
Guaranteed Compatibility
This module is a direct replacement for a wide range of GM vehicles and part numbers. Please verify your part number is on this list or that your vehicle is listed below for a guaranteed fit.
This part is a direct replacement for the following part numbers: 12569773, 12588650, 12589311, 12589585, 12591647, 12591648, 12593531, 12593532, 12594430, 12594431, 12596783, 12596784, 12597521, 12597776, 12597777, 12600818, 12604438, 12604439, 12606369, 12606373, 12606374, 12606398, 12606399, 19209820, 19209821
This Electronic Control Module fits:
- โ 2004-2006 Chevrolet Colorado (RH firewall)
- โ 2004-2006 GMC Canyon (RH firewall)
- โ 2006 Hummer H3 (RH firewall)
- โ 2006 Isuzu I-280 (RH firewall)
- โ 2006 Isuzu I-350 (RH firewall)
- โ 2006 Buick Rainier (4.2L, LH engine)
- โ 2006 Chevrolet Trailblazer & Trailblazer EXT (4.2L, LH engine)
- โ 2006 GMC Envoy & Envoy XL (4.2L, LH engine)
- โ 2006 Isuzu Ascender (4.2L, LH engine)
- โ 2006 Saab 9-7X (6 cylinder, LH engine)