Restore Peak Performance to Your Isuzu Truck
If you’re dealing with a frustrating check engine light, poor fuel economy, or unpredictable engine behavior in your 2006 Isuzu I-350, a failing Powertrain Control Module (PCM) is often the culprit. As an experienced technician, I’ve seen how a faulty engine computer can turn a reliable truck into a source of constant headaches. This isn’t just a replacement part; it’s a reliable, long-term solution. We provide a professionally programmed PCM, flashed with the latest GM-authorized software specifically for your truck’s Vehicle Identification Number (VIN). This ensures seamless integration and restores the precise engine and transmission control your vehicle had when it left the factory.
Case Study: A Tricky Diagnosis
I remember a 2006 Chevy Colorado (which shares the same platform as the I-350) that came into my bay with an issue that had stumped two other shops. The owner complained of random stalling at stoplights and a persistent P0606 (PCM Processor Fault) code that would return days after being cleared. We checked all the usual suspects—wiring, grounds, sensors—and everything looked perfect. On a hunch, we swapped in a known-good, correctly programmed PCM. The truck ran flawlessly for a week of test drives. The original PCM had an internal, heat-sensitive fault that only appeared under specific operating conditions. This experience solidified for me how critical a fully functional, correctly programmed 2006 Isuzu I-350 PCM is for vehicle reliability.
Is Your Truck Showing These Symptoms?
A failing PCM can manifest in various ways. If you’re experiencing any of the following, your engine computer is the likely cause:
- ✔ Persistent Check Engine Light (CEL)
- ✔ Diagnostic Trouble Codes (DTCs) such as P0601, P0602, P0606, or U0100
- ✔ Vehicle won’t start or is difficult to start
- ✔ Rough or erratic idling
- ✔ Poor acceleration and loss of power
- ✔ Decreased fuel efficiency
- ✔ Harsh or incorrect automatic transmission shifting
A Straightforward Guide to Installation
One of the biggest benefits of our service is that you can perform this repair yourself, saving hundreds on dealership labor. The process is direct and requires basic hand tools.
- Safety First: Always disconnect the negative terminal from your vehicle’s battery before starting any electrical work.
- Locate the Module: On your 2006 Isuzu I-350, the PCM is located on the right-hand (passenger side) firewall in the engine bay.
- Disconnect Connectors: Carefully unclip and remove the electrical wiring harnesses connected to the old PCM. These connectors have locking tabs that need to be released.
- Remove the Old PCM: Unbolt the mounting hardware holding the module to the firewall and remove it from the vehicle.
- Install the New PCM: Mount your new, pre-programmed PCM in the same location and secure it with the original hardware.
- Reconnect Everything: Firmly plug the wiring harnesses back into the new module until they click into place. Reconnect the negative battery terminal.
- Final Step: In some cases, a security or CASE (Crankshaft Angle Sensor Error) relearn procedure may be needed. This can often be done with a capable scan tool or by following a specific drive cycle.
Verified Vehicle Compatibility
This module is a direct-fit replacement for a wide range of GM trucks and SUVs. Please verify your vehicle is on this list:
- Chevrolet Colorado 2004-2006 (RH firewall)
- Chevrolet Trailblazer & Trailblazer EXT 2006 (4.2L, LH engine)
- GMC Canyon 2004-2006 (RH firewall)
- GMC Envoy, Envoy XL 2006 (4.2L, LH engine)
- Buick Rainier 2006 (4.2L, LH engine)
- Hummer H3 2006 (RH firewall)
- Isuzu Ascender 2006 (4.2L, LH engine)
- Isuzu I-280 2006 (RH firewall)
- Isuzu I-350 2006 (RH firewall)
- Saab 9-7X 2006 (6-cylinder, ID 12569773 or 12597521)
This part is a direct replacement for service numbers: 12569773, 12588650, 12589311, 12589585, 12591647, 12591648, 12593531, 12593532, 12594430, 12594431, 12596783, 12596784, 12597521, 12597776, 12597777, 12600818, 12604438, 12604439, 12606369, 12606373, 12606374, 12606398, 12606399, 19209820, 19209821.
What is the process after I place my order?
What is the process after I place my order?
After your purchase, you will need to send us your vehicle’s 17-digit VIN. We cannot ship the module until we have this information. Once we receive your VIN, we will program the PCM with the latest GM software specific to your truck and ship it out to you, typically within 1-2 business days.
Do I need a mechanic to install this?
No, this is designed to be a plug-and-play solution. Because we program it to your VIN before shipping, you do not need to take it to a dealership for programming. Installation is straightforward for a confident DIYer with basic tools. See our installation guide above.
Will this 2006 Isuzu I-350 PCM fix my check engine light?
If the check engine light is caused by an internal failure of the PCM itself (indicated by codes like P0601, P0606, etc.), then this module will resolve the issue. However, if the light is on due to a faulty sensor or other component, that separate issue will still need to be addressed.
Is this a used part?
This is a quality, tested, and verified component sourced from recycled vehicles. Each module undergoes a thorough inspection and is then programmed with fresh, vehicle-specific software to ensure it performs to OEM standards. It’s a reliable and cost-effective alternative to a new dealer part.