Restore Your Truck’s Performance and Reliability
As a technician with over two decades of experience under the hood, I’ve seen firsthand the frustration a failing Powertrain Control Module (PCM) can cause. Your 2006 Isuzu I-350 might be experiencing bizarre, hard-to-diagnose issues—from a persistent Check Engine Light to erratic shifting or even a no-start condition. These aren’t just annoyances; they’re signs that the brain of your vehicle’s engine and transmission is struggling. This module is the definitive solution, arriving at your door fully programmed with the latest GM software updates, specifically matched to your truck’s VIN.
Forget the expensive dealership visits and the hassle of coordinating programming. We handle the critical software flashing process for you. When you install this module, you’re not just replacing a faulty part; you’re restoring the precise fuel delivery, ignition timing, and transmission control that your vehicle had when it was new. This is the most direct path to resolving those complex electronic issues and getting your dependable truck back on the road.
From the Diagnostic Bay: The Ghost in the Transmission
A customer brought in a 2006 Trailblazer—which uses this exact same PCM platform—complaining of harsh, unpredictable shifting and a flashing Check Engine Light. They had already replaced the transmission solenoids with no luck. My scan tool showed a generic transmission communication error, U0101. Instead of chasing electrical ghosts for hours, my experience pointed to the PCM. The internal processors that control the transmission logic were failing. After installing one of our pre-programmed PCMs, the shifting immediately smoothed out, and the code never returned. It’s a classic case I’ve seen dozens of times; what seems like a major transmission failure is often a faulty module.
Is Your Truck Showing These Symptoms?
A failing PCM can manifest in numerous ways. If you’re experiencing any of the following, this module is the likely solution:
- ✔ Persistent Check Engine Light (CEL)
- ✔ Diagnostic Trouble Codes (DTCs) for internal module failure, such as P0601, P0606, or other P06xx codes.
- ✔ Unexplained communication errors (U-codes) with other modules.
- ✔ Engine cranks but refuses to start.
- ✔ Rough or unstable idle.
- ✔ Poor fuel economy.
- ✔ Harsh or erratic automatic transmission shifting.
- ✔ The vehicle fails to pass an emissions test.
A Straightforward Guide to Installation
Installing your new 2006 Isuzu I-350 PCM is a job most DIYers can handle with basic tools. Follow these steps carefully for a smooth installation.
- Safety First: Disconnect the negative terminal from your vehicle’s battery and secure it away from the post to prevent accidental reconnection.
- Locate the Module: On your Isuzu I-350, the PCM is typically located on the right-hand (passenger side) firewall in the engine bay.
- Disconnect the Connectors: Carefully release the locking tabs on the electrical wiring harnesses and pull them straight out from the module. Avoid pulling on the wires themselves.
- Remove the Old PCM: Unbolt the mounting hardware that secures the old module to the firewall. Keep the hardware, as you will need it for the new module.
- Install the New PCM: Mount your new, pre-programmed PCM using the original hardware. Ensure it is secure.
- Reconnect Everything: Plug the wiring harnesses firmly back into the new module until they click and lock into place. Reconnect the negative battery terminal.
- Final Step: Some vehicles may require a security relearn procedure, which can often be completed without special tools. Instructions are widely available online or in service manuals for your specific vehicle. Start the engine and check for proper operation.
Verified Vehicle Compatibility
This module is a direct-fit replacement for a wide range of GM vehicles, ensuring broad compatibility. Please verify your vehicle is on this list. This part is compatible with service numbers: 12569773, 12588650, 12589311, 12589585, 12591647, 12591648, 12593531, 12593532, 12594430, 12594431, 12596783, 12596784, 12597521, 12597776, 12597777, 12600818, 12604438, 12604439, 12606369, 12606373, 12606374, 12606398, 12606399, 19209820, 19209821.
- Chevrolet Colorado 2004-2006 (RH firewall)
- GMC Canyon 2004-2006 (RH firewall)
- Hummer H3 2006 (RH firewall)
- Isuzu I-280 2006 (RH firewall)
- Isuzu I-350 2006 (RH firewall)
- Buick Rainier 2006 (4.2L, LH engine)
- Chevrolet Trailblazer 2006 (4.2L, LH engine)
- Chevrolet Trailblazer EXT 2006 (4.2L, LH engine)
- GMC Envoy 2006 (4.2L, LH engine)
- GMC Envoy XL 2006 (4.2L, LH engine)
- Isuzu Ascender 2006 (4.2L, LH engine)
- Saab 9-7X 2006 (6 cylinder, ID 12569773 or 12597521, LH engine)
What is VIN programming and why is it necessary?
What is VIN programming and why is it necessary?
VIN programming is the process of loading your vehicle’s specific software and settings into the PCM. This includes information about your engine, transmission, and factory options. It’s essential for the module to communicate correctly with your vehicle, ensuring proper performance and preventing compatibility issues. We do this for you before shipping.
Do I need to do anything else after I install this part?
In most cases, this is a plug-and-play installation. However, some GM vehicles may require a simple security relearn procedure to sync the new PCM with the anti-theft system. This procedure typically involves a series of key turns and can be done in your driveway without any special scan tools.
Will this fix my check engine light?
If the check engine light is caused by a faulty PCM (e.g., codes P0601-P0606), then yes, this module is the correct fix. If the light is on for another reason, like a bad oxygen sensor, you will still need to repair that separate issue. This module resolves all internal computer-related faults.
How do I provide my VIN?
After you complete your purchase, you will need to send us your vehicle’s 17-digit Vehicle Identification Number (VIN). We will provide clear instructions on how to do this. We cannot program and ship your module without it.